Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.60 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | GAA | P10253 | 9/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132318 | 0.94 | MEN1 (0.67) | MEN1KMT2APOLBCDK5CDK5R1 | |
| SCHEMBL1132320 | 0.94 | MEN1 (0.67) | MEN1KMT2APOLBCDK5CDK5R1 | |
| SCHEMBL12506271 | 0.79 | MEN1 (0.59) | MEN1KMT2APOLBCDK5CDK5R1 | |
| SCHEMBL1132128 | 0.78 | MAPT (0.63) | MEN1KMT2APOLBCDK5CDK5R1 | |
| SCHEMBL1132158 | 0.78 | MAPT (0.63) | MEN1KMT2APOLBCDK5CDK5R1 | |
| SCHEMBL1132724 | 0.78 | MEN1 (0.60) | MEN1KMT2APOLBCDK5CDK5R1 | |
| SCHEMBL1133032 | 0.78 | MEN1 (0.60) | MEN1KMT2APOLBCDK5CDK5R1 | |
| SCHEMBL13583368 | 0.77 | MEN1 (0.50) | MEN1KMT2APOLBCDK5CDK5R1 | |
| SCHEMBL13583364 | 0.77 | MEN1 (0.50) | MEN1KMT2APOLBCDK5CDK5R1 | |
| SCHEMBL1132877 | 0.76 | MEN1 (0.63) | MEN1KMT2APOLBCDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020883-A9 | ENHANCERS OF PROTEIN DEGRADATION | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2012-07-12 | — | — | WO | disclosed |