Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2688412 | 0.88 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL13194440 | 0.84 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL12982931 | 0.83 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL12982649 | 0.81 | TRPV1 (0.45) | TRPV1 | |
| SCHEMBL12982392 | 0.80 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL658222 | 0.80 | KLKB1 (0.49) | TRPV1 | |
| SCHEMBL14658587 | 0.80 | TRPV1 (0.58) | TRPV1 | |
| SCHEMBL12982836 | 0.80 | TRPV1 (0.62) | TRPV1 | |
| SCHEMBL12982481 | 0.79 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL12982827 | 0.79 | TRPV1 (0.54) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606033-A1 | SUBSTITUTED CYCLIC CARBOXAMIDE AND UREA DERIVATIVES AS LIGANDS OF THE VANILLOID RECEPTOR | Grünenthal GmbH (DE) | 2013-06-26 | — | — | EP | disclosed |
| WO-2012022487-A1 | SUBSTITUTED CYCLIC CARBOXAMIDE AND UREA DERIVATIVES AS LIGANDS OF THE VANILLOID RECEPTOR | Grünenthal GmbH (DE) | 2012-02-23 | — | — | WO | disclosed |