Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 8/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1250894 | 1.00 | ATM (0.47) | ATMACEREN | |
| SCHEMBL1250891 | 1.00 | ATM (0.47) | ATMACEREN | |
| SCHEMBL28531386 | 1.00 | ATM (0.47) | ATMACEREN | |
| SCHEMBL28485257 | 0.83 | ATM (0.69) | ATMACEREN | |
| SCHEMBL18187482 | 0.83 | ATM (0.69) | ATMACEREN | |
| SCHEMBL21441513 | 0.83 | ATM (0.69) | ATMACEREN | |
| SCHEMBL18187464 | 0.83 | ATM (0.69) | ATMACEREN | |
| SCHEMBL18187463 | 0.83 | ATM (0.69) | ATMACEREN | |
| SCHEMBL4278865 | 0.80 | ATM (0.70) | ATMACE | |
| SCHEMBL1249542 | 0.80 | ATM (0.70) | ATMACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542521-B | RAD51 inhibitors | 赛泰尔治疗公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-114057740-A | Spirocyclic pyrimidone derivatives, preparation method, pharmaceutical composition and application thereof | 上海赛默罗生物科技有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-104892490-B | For the compound for the midbody compound for preparing optical activity diazocine alkane derivatives | 明治制果药业株式会社 | 2017-07-21 | — | — | CN | disclosed |
| CN-103328476-B | Optically active diazacyclooctane derivative and preparation method thereof | 明治制果药业株式会社 | 2016-12-28 | — | — | CN | disclosed |
| WO-2016089722-A1 | HYDROXYMETHYL PIPERIDINE OREXIN RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2016-06-09 | — | — | WO | disclosed |
| EP-2279737-B1 | Heterocyclic compounds that are active as beta lactamase inhibitors | NOVEXEL (FR) | 2012-10-31 | — | — | EP | disclosed |
| EP-2279737-A1 | Heterocyclic compounds that are active as beta lactamase inhibitors | NOVEXEL (FR) | 2011-02-02 | — | — | EP | disclosed |
| EP-1480644-B1 | NOVEL HETEROCYCLIC COMPOUNDS WHICH ARE ACTIVE AS INHIBITORS OF BETA+LACTAMASES | NOVEXEL (FR) | 2010-10-13 | — | — | EP | disclosed |
| EP-1480644-A2 | NOVEL HETEROCYCLIC COMPOUNDS WHICH ARE ACTIVE AS INHIBITORS OF BETA+LACTAMASES | Aventis Pharma S.A. (FR) | 2004-12-01 | — | — | EP | disclosed |
| EP-1307457-B1 | AZABICYCLIC COMPOUNDS, PREPARATION THEREOF AND USE AS MEDICINES, IN PARTICULAR AS ANTIBACTERIAL AGENTS | AVENTIS PHARMA SA (FR) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003063864-A2 | HETEROCYCLIC COMPOUNDS WHICH ARE ACTIVE AS INHIBITORS OF BETA LACTAMASES | AVENTIS PHARMA S.A. (FR) | 2003-08-07 | — | — | WO | disclosed |