Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 5/20 | 0.48 |
| ▸ | MGAM | O43451 | 3/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12509569 | 0.93 | DYRK1A (0.57) | HDAC6DYRK1AKDM4ENPC1PKM | |
| SCHEMBL12508993 | 0.91 | APP (0.60) | APPGLAGAASULT1A1 | |
| SCHEMBL12509576 | 0.84 | APP (0.68) | HDAC6DYRK1AKDM4ENPC1PKM | |
| SCHEMBL10311784 | 0.83 | APP (0.69) | KDM4ENPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL12509030 | 0.82 | APP (0.70) | HDAC6DYRK1AKDM4ENPC1PKM | |
| SCHEMBL12509376 | 0.82 | APP (0.70) | HDAC6DYRK1AKDM4ENPC1PKM | |
| SCHEMBL12509551 | 0.82 | SCD (0.54) | HDAC6DYRK1AKDM4ENPC1PKM | |
| SCHEMBL12509024 | 0.81 | APP (0.55) | APPMGAMGLAGAASULT1A1 | |
| SCHEMBL2136362 | 0.81 | SMN1; SMN2 (0.71) | HDAC6DYRK1AKDM4ENPC1PKM | |
| SCHEMBL12509567 | 0.76 | APP (0.54) | APPGLAGAASULT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | MAPT, PRNP, MAP4 | HDAC6 61/4885DYRK1A 3284/4885KDM4E 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.