Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.78 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.69 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.69 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.69 |
| ▸ | TSPO | P30536 | 1/20 | 0.69 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.69 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.69 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | P2RY10 | O00398 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GMNN | O75496 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | CETP | P11597 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sphingosylphosphorylchloline SCHEMBL196365 | 1.00 | MEN1 (0.78) | MEN1KMT2AS1PR1S1PR4S1PR3 | |
| Sphingosylphosphorylchloline SCHEMBL196291 | 0.99 | MEN1 (0.77) | MEN1KMT2AS1PR1S1PR4S1PR3 | |
| Sphingosylphosphorylchloline SCHEMBL195873 | 0.99 | MEN1 (0.77) | MEN1KMT2AS1PR1S1PR4S1PR3 | |
| SCHEMBL17696724 | 0.90 | S1PR1 (0.77) | MEN1KMT2AS1PR1S1PR4S1PR3 | |
| SCHEMBL17775054 | 0.88 | S1PR1 (0.62) | MEN1KMT2AS1PR1S1PR4S1PR3 | |
| Sphingosylphosphorylchloline SCHEMBL195431 | 0.88 | S1PR1 (1.00) | MEN1KMT2AS1PR1S1PR4S1PR3 | |
| Sphingosylphosphorylchloline SCHEMBL19928025 | 0.88 | S1PR1 (1.00) | MEN1KMT2AS1PR1S1PR4S1PR3 | |
| SCHEMBL31427625 | 0.88 | S1PR1 (1.00) | MEN1KMT2AS1PR1S1PR4S1PR3 | |
| SCHEMBL29602895 | 0.87 | S1PR1 (0.73) | MEN1KMT2AS1PR1S1PR4S1PR3 | |
| SCHEMBL14095793 | 0.85 | S1PR1 (0.58) | MEN1KMT2AS1PR1S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110177156-A1 | Sterol-Modified Amphiphilic Lipids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2011-07-21 | — | — | US | disclosed |
| WO-2009064696-A1 | STEROL-MODIFIED AMPHIPHILIC LIPIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177156-A1 | Sterol-Modified Amphiphilic Lipids | SREBF1, SREBF2, SGMS1 | MEN1 1960/4885KMT2A 4672/4885S1PR1 242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.