Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 19/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252188 | 0.93 | PARP1 (0.54) | PARP1 | |
| Hydrochloric Acid SCHEMBL1249915 | 0.89 | PARP1 (0.60) | PARP1 | |
| Hydrochloric Acid SCHEMBL1252033 | 0.85 | PARP1 (0.55) | PARP1 | |
| SCHEMBL1252640 | 0.83 | PARP1 (0.57) | PARP1 | |
| SCHEMBL1249820 | 0.83 | PARP1 (0.57) | PARP1 | |
| Hydrochloric Acid SCHEMBL1251401 | 0.83 | PARP1 (0.53) | PARP1 | |
| SCHEMBL1252279 | 0.82 | PARP1 (0.58) | PARP1 | |
| SCHEMBL1249814 | 0.82 | PARP1 (0.49) | PARP1 | |
| Hydrochloric Acid SCHEMBL1251317 | 0.81 | PARP1 (0.48) | PARP1 | |
| SCHEMBL1249911 | 0.80 | PARP1 (0.52) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2281818-A1 | Fused pyridazine derivative compounds and drugs containing these compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-02-09 | — | — | EP | claimed |