Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CD38 | P28907 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536111 | 0.84 | PRKCI (0.53) | MKNK1MKNK2DYRK1ACD38FYN | |
| SCHEMBL16298860 | 0.82 | HRH3 (0.52) | DYRK1ACD38CHEK1CHEK2CARM1 | |
| SCHEMBL13637132 | 0.80 | CD38 (0.42) | DYRK1ACD38CARM1PRMT1CYP17A1 | |
| SCHEMBL27811249 | 0.79 | DYRK1A (0.38) | DYRK1ACD38CHEK1CHEK2CARM1 | |
| SCHEMBL5179594 | 0.77 | ESR1 (0.50) | MKNK1MKNK2DYRK1ACHEK1CHEK2 | |
| SCHEMBL9454357 | 0.76 | PRKCI (0.41) | MKNK1MKNK2DYRK1ACD38FYN | |
| SCHEMBL12936656 | 0.76 | CARM1 (0.46) | DYRK1ACD38CARM1PRMT1CYP17A1 | |
| SCHEMBL13625432 | 0.76 | CD38 (0.40) | DYRK1ACD38PTGS1CARM1PRMT1 | |
| SCHEMBL10034581 | 0.74 | SLC6A2 (0.47) | DYRK1ACD38CARM1PRMT1PRMT5 | |
| SCHEMBL1872880 | 0.74 | DYRK1A (0.55) | DYRK1ACD38CHEK1CHEK2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084345-A1 | A METHOD FOR RAPIDLY EVALUATING PERFORMANCE OF SHORT INTERFERING RNA WITH NOVEL CHEMICAL MODIFICATIONS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | WO | disclosed |
| EP-1970377-A1 | LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2008-09-17 | — | — | EP | disclosed |