Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNNI3K | Q59H18 | 20/20 | 0.78 |
| ▸ | EGFR | P00533 | 7/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12517883 | 0.92 | TNNI3K (0.88) | TNNI3KEGFR | |
| SCHEMBL12517528 | 0.88 | TNNI3K (1.00) | TNNI3KEGFR | |
| SCHEMBL2227166 | 0.87 | TNNI3K (1.00) | TNNI3KEGFR | |
| SCHEMBL14323816 | 0.86 | TNNI3K (0.80) | TNNI3KEGFR | |
| SCHEMBL12517917 | 0.86 | TNNI3K (0.82) | TNNI3KEGFR | |
| Hydrochloric Acid SCHEMBL14322631 | 0.85 | TNNI3K (0.79) | TNNI3KEGFR | |
| SCHEMBL12516268 | 0.84 | TNNI3K (1.00) | TNNI3KEGFR | |
| SCHEMBL12517918 | 0.84 | TNNI3K (0.75) | TNNI3KEGFR | |
| Hydrochloric Acid SCHEMBL14324498 | 0.83 | TNNI3K (0.97) | TNNI3KEGFR | |
| SCHEMBL2275752 | 0.83 | TNNI3K (1.00) | TNNI3KEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088027-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-07-21 | — | — | WO | disclosed |