Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14498526 | 0.80 | USP2 (0.54) | USP2KDM4EALDH1A1ANPEPKMT2A | |
| SCHEMBL13274699 | 0.80 | USP2 (0.54) | USP2KDM4EALDH1A1ANPEPHSD17B10 | |
| SCHEMBL4494214 | 0.77 | USP2 (0.56) | USP2KDM4EALDH1A1ANPEPHSD17B10 | |
| SCHEMBL4494210 | 0.77 | USP2 (0.50) | USP2KDM4EALDH1A1ANPEPHSD17B10 | |
| SCHEMBL4501019 | 0.77 | USP2 (0.50) | USP2KDM4EALDH1A1ANPEPHSD17B10 | |
| SCHEMBL4501023 | 0.77 | USP2 (0.56) | USP2KDM4EALDH1A1ANPEPHSD17B10 | |
| SCHEMBL3059739 | 0.75 | USP2 (0.54) | USP2KDM4EALDH1A1ANPEPKMT2A | |
| SCHEMBL1055186 | 0.75 | — | — | |
| SCHEMBL19125455 | 0.75 | — | — | |
| SCHEMBL200033 | 0.74 | USP2 (0.58) | USP2KDM4EALDH1A1ANPEPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103282025-B | Melt-extruded solid dispersions containing apoptosis-inducing agents | 艾伯维爱尔兰无限公司 | 2018-01-02 | — | — | CN | disclosed |
| WO-2011084402-A1 | TYROSINE KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | WO | disclosed |