Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1251900 | 0.96 | PARP1 (0.58) | PARP1 | |
| SCHEMBL1251351 | 0.88 | PARP1 (0.57) | PARP1 | |
| SCHEMBL1251941 | 0.87 | PARP1 (0.56) | PARP1 | |
| SCHEMBL1249699 | 0.87 | PARP1 (0.56) | PARP1 | |
| Hydrochloric Acid SCHEMBL1252144 | 0.87 | PARP1 (0.56) | PARP1 | |
| SCHEMBL1249649 | 0.87 | PARP1 (0.50) | PARP1 | |
| SCHEMBL4918497 | 0.86 | PARP1 (0.57) | PARP1 | |
| SCHEMBL1251303 | 0.85 | PARP1 (0.52) | PARP1 | |
| SCHEMBL1252635 | 0.85 | PARP1 (0.54) | PARP1 | |
| SCHEMBL1252600 | 0.85 | PARP1 (0.53) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2281818-A1 | Fused pyridazine derivative compounds and drugs containing these compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-02-09 | — | — | EP | claimed |
| US-7402580-B2 | Fused pyridazine derivative compounds and drugs containing these compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-07-22 | — | — | US | claimed |