Trioxsalen

Trioxsalen

SCHEMBL1252

Cc1cc2cc3c(C)cc(=O)oc3c(C)c2o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 1.00
ALDH1A1 P00352 6/20 1.00
MAPK1 P28482 3/20 1.00
MAOA P21397 2/20 1.00
CYP1A2 P05177 2/20 1.00
CYP3A4 P08684 2/20 1.00
HTR2C P28335 1/20 1.00
ADORA2A P29274 1/20 1.00
MAOB P27338 2/20 0.53
CYP1A1 P04798 1/20 0.49
CYP1B1 Q16678 1/20 0.49
HSD17B10 Q99714 5/20 0.47
L3MBTL1 Q9Y468 4/20 0.47
HPGD P15428 4/20 0.47
TSHR P16473 2/20 0.47
MAPT P10636 3/20 0.46
UBE2N P61088 1/20 0.46
KMT2A Q03164 2/20 0.45
LMNA P02545 6/20 0.43
HTT P42858 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trioxsalen SCHEMBL4954831 1.00 KDM4E (1.00) KDM4EALDH1A1MAPK1MAOACYP1A2
Trioxsalen SCHEMBL29432841 1.00 KDM4E (1.00) KDM4EALDH1A1MAPK1MAOACYP1A2
Trioxsalen SCHEMBL11442670 0.98 KDM4E (0.97) KDM4EALDH1A1MAPK1MAOACYP1A2
Trioxsalen SCHEMBL28285134 0.92 KDM4E (0.85) KDM4EALDH1A1MAPK1MAOACYP1A2
Trioxsalen SCHEMBL28103198 0.92 KDM4E (0.85) KDM4EALDH1A1MAPK1MAOACYP1A2
Trioxsalen SCHEMBL28089383 0.92 KDM4E (0.85) KDM4EALDH1A1MAPK1MAOACYP1A2
Trioxsalen SCHEMBL28215231 0.92 KDM4E (0.85) KDM4EALDH1A1MAPK1MAOACYP1A2
Trioxsalen SCHEMBL28143570 0.90 KDM4E (0.81) KDM4EALDH1A1MAPK1MAOACYP1A2
Trioxsalen SCHEMBL28205170 0.90 KDM4E (0.81) KDM4EALDH1A1MAPK1MAOACYP1A2
Trioxsalen SCHEMBL28165974 0.87 KDM4E (0.76) KDM4EALDH1A1MAPK1MAOACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 260324 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388642-A1 COMPOSITIONS AND METHODS FOR IMPROVED NK CELL THERAPIES CERUS CORPORATION (US) 2025-12-25 US claimed
US-20250177534-A1 THERMOSTABLE UV INACTIVATED VACCINES AND OTHER BIOPHARMACEUTICALS UNIVERSAL STABILIZATION TECHNOLOGIES INC. (US) 2025-06-05 US claimed
EP-4405495-A1 PHOTOREACTIVE AND CLEAVABLE PROBES FOR TAGGING BIOMOLECULES Syncell ( Taiwan) Inc. (TW) 2024-07-31 EP claimed
CN-115568391-B Method for promoting rapid growth of bulbil konjak foliar corms to produce seed konjak 安康市农业科学研究院 2024-07-23 CN claimed
US-12044974-B2 Compositions for removing photoresists and methods of manufacturing semiconductor devices and semiconductor packages using the compositions SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-07-23 US claimed
US-12043705-B2 Pigment dispersant for coating BASF COATINGS GMBH (DE) 2024-07-23 US claimed
US-12044967-B2 Actinic-ray-sensitive or radiation-sensitive resin composition, resist film, pattern formation method, and method for manufacturing electronic device FUJIFILM CORPORATION (JP) 2024-07-23 US claimed
CN-221381417-U Emergency communication cabinet 长春市天空标通信有限公司 2024-07-19 CN claimed
US-20240240047-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2024-07-18 US claimed
US-20240239820-A1 ORGANOMETALLIC COMPOUND, RESIST COMPOSITION INCLUDING THE SAME AND PATTERN FORMING METHOD USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-07-18 US claimed
US-3950407-A Process for preparing dibenzo[a,d]cycloheptenes RIKER LABORATORIES, INCORPORATED (US) 1976-04-13 US claimed
US-3946017-A PRESSURE SENSITIVE MATERIALS BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-03-23 US claimed
US-3942467-A Time temperature indicator BIO-MEDICAL SCIENCES, INC. (US) 1976-03-09 US claimed
US-3941880-A Method for use of 11-lower alkyl steroids G. D. SEARLE & CO. (US) 1976-03-02 US claimed
US-3937864-A HEAT-SENSITIVE RECORDING SHEETS HAVING IMPROVED STABILITY MITSUBISHI PAPER MILLS, LTD. (JA) 1976-02-10 US claimed
US-3936446-A Isocyanocephalosporanates BEECHAM GROUP LIMITED (DT) 1976-02-03 US claimed
US-3936564-A Pressure-sensitive copying paper containing lactone compounds of pyridine-carboxylic acid HODOGAYA CHEMICAL CO., LTD. (JA) 1976-02-03 US claimed
US-3932510-A BY ISOMERIZATION OF DELTA-ENOL LACTONE HOECHST AKTIENGESELLSCHAFT (DT) 1976-01-13 US claimed
US-3930672-A Pressure-sensitive copying paper containing lactone compounds derived from pyridine-carboxylic acid HODOGAYA CHEMICAL CO., LTD. (JA) 1976-01-06 US claimed
US-3931182-A Lactones of the diazaxanthene series, their production and their use as dye-forming components for copying methods BASF AKTIENGESELLSCHAFT (DT) 1976-01-06 US claimed