Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 13/20 | 0.47 |
| ▸ | PAK4 | O96013 | 3/20 | 0.47 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.41 |
| ▸ | TTBK1 | Q5TCY1 | 5/20 | 0.39 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11970647 | 0.93 | MAP3K14 (0.47) | MAP3K14PAK4PIKFYVEPRKD1TTBK1 | |
| SCHEMBL11970639 | 0.88 | PAK4 (0.52) | MAP3K14PAK4PIKFYVEPRKD1TTBK1 | |
| SCHEMBL11971109 | 0.86 | MAP3K14 (0.49) | MAP3K14PAK4PIKFYVEPRKD1TTBK1 | |
| SCHEMBL11970868 | 0.85 | PAK4 (0.46) | MAP3K14PAK4PIKFYVEPRKD1TTBK1 | |
| SCHEMBL11970625 | 0.85 | MAP3K14 (0.44) | MAP3K14PAK4PIKFYVEPRKD1TTBK1 | |
| SCHEMBL12525999 | 0.83 | MAP3K14 (0.40) | MAP3K14PAK4PIKFYVE | |
| SCHEMBL11970518 | 0.83 | PAK4 (0.44) | MAP3K14PAK4PIKFYVEPRKD1TTBK1 | |
| SCHEMBL11970497 | 0.82 | PAK4 (0.55) | MAP3K14PAK4PIKFYVEPRKD1TTBK1 | |
| SCHEMBL11970738 | 0.82 | MAP3K14 (0.46) | MAP3K14PAK4PIKFYVEPRKD1TTBK1 | |
| SCHEMBL11970819 | 0.82 | MAP3K14 (0.46) | MAP3K14PAK4PIKFYVEPRKD1TTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012123522-A1 | 6,5-HETEROCYCLIC PROPARGYLIC ALCOHOL COMPOUNDS AND USES THEREFOR | F. HOFFMANN-LA ROCHE AG (CH) | 2012-09-20 | — | — | WO | disclosed |