SCHEMBL125249

SCHEMBL125249

O=C(O)C(=O)Cc1c[nH]c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 1.00
KMT2A Q03164 7/20 1.00
MAPT P10636 6/20 1.00
KDM4E B2RXH2 4/20 1.00
SMN1; SMN2 Q16637 3/20 1.00
ALDH1A1 P00352 2/20 1.00
HPGD P15428 1/20 1.00
SLC6A2 P23975 1/20 0.77
FNTA P49354 1/20 0.77
FNTB P49356 1/20 0.77
LMNA P02545 3/20 0.62
PKM P14618 1/20 0.59
CYP3A4 P08684 2/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2C19 P33261 1/20 0.57
APAF1 O14727 1/20 0.56
POLB P06746 1/20 0.56
RECQL P46063 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
MPO P05164 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362070 1.00 MEN1 (1.00) MEN1KMT2AMAPTKDM4ESMN1; SMN2
SCHEMBL27763159 1.00 MEN1 (1.00) MEN1KMT2AMAPTKDM4ESMN1; SMN2
SCHEMBL4662759 0.98 MEN1 (0.97) MEN1KMT2AMAPTKDM4ESMN1; SMN2
SCHEMBL9494228 0.98 MEN1 (0.97) MEN1KMT2AMAPTKDM4ESMN1; SMN2
Ammonia Solution, Strong SCHEMBL18582291 0.98 MEN1 (0.97) MEN1KMT2AMAPTKDM4ESMN1; SMN2
Lactic Acid SCHEMBL27789008 0.90 MAPT (0.81) MEN1KMT2AMAPTKDM4ESMN1; SMN2
SCHEMBL4620881 0.90 MAPT (0.81) MEN1KMT2AMAPTKDM4ESMN1; SMN2
Kurasoin B SCHEMBL29489947 0.87 SLC6A2 (1.00) MEN1KMT2AMAPTKDM4ESMN1; SMN2
Dl-Tryptophan SCHEMBL2174790 0.86 KDM4E (0.82) MEN1KMT2AMAPTKDM4ESMN1; SMN2
D-Tryptophan SCHEMBL2176030 0.86 KDM4E (0.82) MEN1KMT2AMAPTKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2138 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4739326-A2 PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA SNIPR Biome ApS (DK) 2026-05-13 EP claimed
US-20260123658-A1 Methods of Increasing the Beneficial Properties of Fermented Foods The Brd. of Trustees of the Univ. of Illinois (US) 2026-05-07 US claimed
EP-4677086-A1 PROTECTION OF PLANTS AGAINST PATHOGENS BY INDUCTION OF SYSTEMIC OR LOCALIZED PROTECTIVE RESPONSES IN PLANTS Greenlight Biosciences, Inc. (US) 2026-01-14 EP claimed
EP-4633627-A1 COSMETIC USE OF A COMPOSITION FOR CARING FOR KERATIN MATERIALS COMPRISING AT LEAST INDOLE-3-PYRUVIC ACID L'OREAL (FR) 2025-10-22 EP claimed
US-12435294-B2 Prevention of the oxidation of perfumery raw materials and food raw materials FIRMENICH SA (CH) 2025-10-07 US claimed
US-20250268959-A1 COMPOSITIONS CONTAINING INDOLE-DERIVED METABOLITES AND METHODS OF USE THEREOF Imvela Corp. (US) 2025-08-28 US claimed
US-12318414-B2 Method and system to modify an individual's gut-brain axis to provide neurocognitive protection SEED HEALTH, INC. (US) 2025-06-03 US claimed
CN-120005847-A Alpha-hydroxy-beta-keto acid synthase for catalyzing alpha-keto acid coupling reaction 北京大学 2025-05-16 CN claimed
WO-2025083271-A1 BACTERIAL COMPOSITION COMPRISING AKKERMANSIA SPECIES, FOR IMPROVING THE RESPONSE TO CAR T-CELL THERAPY INSTITUT GUSTAVE ROUSSY (FR) 2025-04-24 WO claimed
EP-0412947-A1 Cosmetic use of 3-indolepyruvic acid POLIFARMA S.p.A. (IT) 1991-02-13 EP claimed
EP-0135846-B1 PRODUCTION OF L-AMINO ACIDS BY TRANSAMINATION GENETICS INSTITUTE, INC. (US) 1990-08-16 EP claimed
EP-0362152-A2 Use of 3-indolepyruvic acid as a pharmaceutical agent for the inhibition of peripheral degenerative pathologies POLIFARMA S.p.A. (IT) 1990-04-04 EP claimed
EP-0106813-B1 PHARMACEUTICAL UTILISATION OF 3-INDOLPYRUVIC ACID POLIFARMA S.p.A. (IT) 1988-12-28 EP claimed
CN-85107547-A Microchemiluminescent detection system 1987-04-15 CN claimed
EP-0175577-A2 Microchemiluminescent assay system Kiel, Jonathan L (US) 1986-03-26 EP claimed
US-4551471-A Use of 3-indolepyruvic acid for increasing serotonin POLIFARMA S.P.A. (IT) 1985-11-05 US claimed
US-4518692-A ALPHA-KETO ACIDS, L-ASPARTIC ACID, TRANSAMINASE GENETICS INSTITUTE, INC. (US) 1985-05-21 US claimed
EP-0135846-A2 Production of L-amino acids by transamination GENETICS INSTITUTE, INC. (US) 1985-04-03 EP claimed
EP-0106813-A2 Pharmaceutical utilisation of 3-indolpyruvic acid POLIFARMA S.p.A. (IT) 1984-04-25 EP claimed