Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 18/20 | 0.81 |
| ▸ | OGA | O60502 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12272910 | 0.90 | FLT3 (1.00) | FLT3 | |
| SCHEMBL12526961 | 0.85 | FLT3 (0.81) | FLT3ACHE | |
| SCHEMBL12272276 | 0.79 | FLT3 (0.83) | FLT3 | |
| SCHEMBL12272706 | 0.79 | FLT3 (1.00) | FLT3ACHE | |
| SCHEMBL12522894 | 0.78 | FLT3 (0.83) | FLT3ACHEBACE1 | |
| SCHEMBL12273002 | 0.78 | FLT3 (0.83) | FLT3ACHEBACE1 | |
| SCHEMBL12272668 | 0.75 | FLT3 (1.00) | FLT3 | |
| SCHEMBL12273236 | 0.74 | FLT3 (1.00) | FLT3 | |
| SCHEMBL12272831 | 0.73 | FLT3 (0.64) | FLT3ACHEBACE1 | |
| SCHEMBL12527715 | 0.73 | FLT3 (0.64) | FLT3ACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012123470-A1 | IMIDAZO PYRAZINES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-09-20 | — | — | WO | disclosed |