Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17770883 | 1.00 | ACE (0.41) | ACEAPPMMEF2F10 | |
| SCHEMBL12527660 | 0.91 | ACE (0.41) | ACEAPPMMEF2F10 | |
| SCHEMBL17771381 | 0.89 | ACE (0.39) | ACEAPPMMEF2F10 | |
| SCHEMBL17770880 | 0.86 | ACE (0.41) | ACEAPPMMEF2F10 | |
| SCHEMBL12528418 | 0.86 | ACE (0.41) | ACEAPPMMEF2F10 | |
| SCHEMBL12494366 | 0.85 | ACE (0.47) | ACEAPPMME | |
| SCHEMBL12495036 | 0.85 | ACE (0.47) | ACEAPPMME | |
| SCHEMBL12528515 | 0.84 | ACE (0.40) | ACEAPPMMEF2F10 | |
| SCHEMBL12494246 | 0.83 | ACE (0.55) | ACEAPPMMEGAABTK | |
| SCHEMBL12494970 | 0.83 | ACE (0.55) | ACEAPPMMEGAABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012125622-A1 | SUBSTITUTED ADIPIC ACID AMIDES AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-09-20 | — | — | WO | disclosed |