⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22164418 | 0.95 | MEN1 (0.41) | — | |
| SCHEMBL27744962 | 0.83 | — | — | |
| SCHEMBL153914 | 0.81 | POLB (0.52) | — | |
| SCHEMBL10015683 | 0.80 | — | — | |
| SCHEMBL177611 | 0.78 | POLB (0.50) | — | |
| SCHEMBL15502205 | 0.78 | POLB (0.50) | — | |
| SCHEMBL16491142 | 0.78 | POLB (0.50) | — | |
| SCHEMBL39378 | 0.78 | POLB (0.50) | — | |
| SCHEMBL7521085 | 0.78 | POLB (0.50) | — | |
| SCHEMBL8753814 | 0.78 | POLB (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105523915-B | A kind of method that high yield gas phase catalysis cracking prepares two fluoracyl fluorides | 山东东岳高分子材料有限公司 | 2017-11-21 | — | — | CN | claimed |
| CN-106831406-B | A kind of method and device of two fluoracyl fluorides of nonmetal catalyzed preparation | 中国科学院上海高等研究院 | 2019-10-11 | — | — | CN | disclosed |
| CN-107867997-A | A kind of method for preparing two fluoracyl fluorides | 中化近代环保化工(西安)有限公司 | 2018-04-03 | — | — | CN | disclosed |
| CN-105523915-B | A kind of method that high yield gas phase catalysis cracking prepares two fluoracyl fluorides | 山东东岳高分子材料有限公司 | 2017-11-21 | — | — | CN | disclosed |
| CN-105523915-B | A kind of method that high yield gas phase catalysis cracking prepares two fluoracyl fluorides | 山东东岳高分子材料有限公司 | 2017-11-21 | — | — | CN | disclosed |
| CN-106831406-A | A kind of nonmetal catalyzed method and device for preparing two fluoracyl fluorides | 中国科学院上海高等研究院 | 2017-06-13 | — | — | CN | disclosed |
| US-9522906-B2 | Tetrahydroquinoline analogues as muscarinic agonists | ACADIA PHARMACEUTICALS, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| CN-105523915-A | Method for high-yield gas-phase catalytic cracking preparation of difluoroacetyl fluoride | SHANDONG DONGYUE POLYMER MAT | 2016-04-27 | — | — | CN | disclosed |
| US-20140221364-A1 | TETRAHYDROQUINOLINE ANALOGUES AS MUSCARINIC AGONISTS | ACADIA PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | US | disclosed |
| US-8680115-B2 | Tetrahydroquinoline analogues as muscarinic agonists | ACADIA PHARMACEUTICALS, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-7955532-B2 | High performance capsules for electrophoretic displays | SIPIX IMAGING, INC. (US) | 2011-06-07 | — | — | US | disclosed |
| US-20090239903-A1 | TETRAHYDROQUINOLINE ANALOGUES AS MUSCARINIC AGONISTS | ACADIA PHARMACEUTICALS, INC. (US) | 2009-09-24 | — | — | US | disclosed |
| US-20090239903-A1 | TETRAHYDROQUINOLINE ANALOGUES AS MUSCARINIC AGONISTS | ACADIA PHARMACEUTICALS, INC. (US) | 2009-09-24 | — | — | US | disclosed |
| US-7550459-B2 | Neurodegenerative diseases, psychological disorders; e.g. 4-[3-(3a -Cyclopropylmethoxy-8-azabicyclo[3.2.1]oct-8-yl)-2-methylpropyl]-4H-benzo[1.4]oxazin-3-one | ACADIA PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7550459-B2 | Neurodegenerative diseases, psychological disorders; e.g. 4-[3-(3a -Cyclopropylmethoxy-8-azabicyclo[3.2.1]oct-8-yl)-2-methylpropyl]-4H-benzo[1.4]oxazin-3-one | ACADIA PHARMACEUTICALS, INC. (US) | 2009-06-23 | — | — | US | disclosed |