Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.73 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920963 | 0.87 | MEN1 (0.82) | MEN1IRAK4KMT2ARAB9ARXFP1 | |
| SCHEMBL1605200 | 0.87 | MEN1 (0.96) | MEN1IRAK4KMT2ARAB9ARXFP1 | |
| SCHEMBL1920737 | 0.86 | MEN1 (0.78) | MEN1IRAK4KMT2ARAB9ARXFP1 | |
| SCHEMBL12734237 | 0.86 | MEN1 (0.80) | MEN1IRAK4KMT2ARAB9ARXFP1 | |
| SCHEMBL1604254 | 0.86 | MEN1 (0.80) | MEN1IRAK4KMT2ARAB9ARXFP1 | |
| SCHEMBL1651778 | 0.86 | MEN1 (0.80) | MEN1IRAK4KMT2ARAB9ARXFP1 | |
| SCHEMBL1604266 | 0.85 | MEN1 (0.77) | MEN1IRAK4KMT2ARAB9ARXFP1 | |
| SCHEMBL1653600 | 0.85 | MEN1 (0.70) | MEN1IRAK4KMT2ARAB9ARXFP1 | |
| SCHEMBL10343392 | 0.85 | MEN1 (1.00) | MEN1IRAK4KMT2ARAB9ARXFP1 | |
| SCHEMBL1652468 | 0.83 | MEN1 (0.76) | MEN1IRAK4KMT2ARAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622914-B1 | NEW PIPERIDINYLAMINO-THIENO[2,3-D] PYRIMIDINE COMPOUNDS | TROVIS PHARMACEUTICALS LLC (US) | 2011-06-01 | — | — | EP | disclosed |