Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.73 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | MTOR | P42345 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
| ▸ | POLA1 | P09884 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.45 |
| ▸ | ALB | P02768 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15316783 | 0.95 | PDE3A (0.80) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL232223 | 0.95 | PDE3A (0.80) | PDE3APDE4DSLC29A1LMNAMTOR | |
| Phosphoric Acid SCHEMBL4576320 | 0.91 | PDE3A (0.73) | PDE3APDE4DSLC29A1LMNAMTOR | |
| Phosphoric Acid SCHEMBL20769295 | 0.91 | PDE3A (0.73) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL1254196 | 0.87 | PDE3A (0.58) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL17184312 | 0.86 | PDE3A (0.67) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL29574822 | 0.85 | PDE3A (0.71) | PDE3APDE4DSLC29A1LMNAMTOR | |
| SCHEMBL32672458 | 0.85 | PDE3A (0.62) | PDE3APDE4DSLC29A1LMNAMTOR | |
| Gemcitabine SCHEMBL12503065 | 0.85 | PDE3A (1.00) | PDE3APDE4DSLC29A1LMNAMTOR | |
| Gemcitabine SCHEMBL6761683 | 0.85 | PDE3A (1.00) | PDE3APDE4DSLC29A1LMNAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879991-B2 | CGRP binding nucleic acids | NOXXON PHARMA AG (DE) | 2011-02-01 | — | — | US | disclosed |
| US-7629447-B2 | Dideoxynucleoside derivatives | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20080064868-A1 | Novel Dideoxynucleoside Derivatives | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20060183700-A1 | Cgrp binding nucleic acids | NOXXON PHARMA AG (DE) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064868-A1 | Novel Dideoxynucleoside Derivatives | DNA2, DDX20, DNASE1 | PDE3A 3110/4885PDE4D 3408/4885SLC29A1 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.