Trans-Phytol

Trans-Phytol

SCHEMBL1254535

C/C(=C\CO)CCC[C@H](C)CCC[C@H](C)CCCC(C)C.CCO

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Trans-Phytol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 0.93
PTGS1 P23219 1/20 0.46
PDE4A P27815 1/20 0.46
SNCA P37840 1/20 0.46
PDE3A Q14432 1/20 0.46
KDM1A O60341 1/20 0.45
LMNA P02545 1/20 0.45
PTPN2 P17706 1/20 0.41
CDC25B P30305 1/20 0.41
BLM P54132 1/20 0.39
MEN1 O00255 2/20 0.39
CYP3A4 P08684 2/20 0.39
ALOX15 P16050 2/20 0.39
KMT2A Q03164 2/20 0.39
ALDH1A1 P00352 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trans-Phytol SCHEMBL14763835 0.96 PTPN1 (1.00) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL8079351 0.96 PTPN1 (1.00) PTPN1PTGS1PDE4ASNCAPDE3A
Trans-Phytol SCHEMBL17962948 0.96 PTPN1 (1.00) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL8070052 0.96 PTPN1 (1.00) PTPN1PTGS1PDE4ASNCAPDE3A
Trans-Phytol SCHEMBL16367020 0.96 PTPN1 (1.00) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL8079353 0.96 PTPN1 (1.00) PTPN1PTGS1PDE4ASNCAPDE3A
Trans-Phytol SCHEMBL22784 0.96 PTPN1 (1.00) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL4718132 0.96 PTPN1 (1.00) PTPN1PTGS1PDE4ASNCAPDE3A
SCHEMBL8079352 0.96 PTPN1 (1.00) PTPN1PTGS1PDE4ASNCAPDE3A
Trans-Phytol SCHEMBL3133654 0.96 PTPN1 (1.00) PTPN1PTGS1PDE4ASNCAPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113636995-A Method for purifying myricetin from waxberry leaves 浙江大学中原研究院 2021-11-12 CN disclosed
CN-107666946-A Chiral isomer separation by SFC 帝斯曼知识产权资产管理有限公司 2018-02-06 CN disclosed
US-20150291943-A1 Polypeptides Having Chlorophyllase Activity and Polynucleotides Encoding Same NOVOZYMES AS (DK) 2015-10-15 US disclosed
EP-2929020-A1 POLYPEPTIDES HAVING CHLOROPHYLLASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME Novozymes A/S (DK) 2015-10-14 EP disclosed
WO-2014143690-A1 METHOD FOR PREPARING (METH)ACRYLATES OF BIOBASED ALCOHOLS AND POLYMERS THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-09-18 WO disclosed
WO-2014086928-A1 POLYPEPTIDES HAVING CHLOROPHYLLASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME NOVOZYMES A/S (DK) 2014-06-12 WO disclosed
EP-2464240-A1 PHYTANIC ACID FRACTIONATION PROCESS, FATTY ACID PRODUCTS AND USE THEREOF K.D. Pharma Bexbach GMBH (DE) 2012-06-20 EP disclosed
US-7897369-B2 Isoprenoid wax ester synthases, isoprenoid acyl CoA-synthetases, and uses thereof REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2011-03-01 US disclosed
WO-2011018096-A1 PHYTANIC ACID FRACTIONATION PROCESS, FATTY ACID PRODUCTS AND USE THEREOF K.D. PHARMA BEXBACH GMBH (DE) 2011-02-17 WO disclosed
US-20110033595-A1 Fatty acid fractionation process, fatty acid products and use thereof K.D. PHARMA BEXBACH GMBH (DE) 2011-02-10 US disclosed
US-20090117629-A1 ISOPRENOID WAX ESTER SYNTHASES, ISOPRENOID ACYL COA-SYNTHETASES, AND USES THEREOF REGENTS OF THE UNIVERSITY OF MINNESOTA 2009-05-07 US disclosed
EP-1047936-A1 PHARMACEUTICAL GRADE SAW PALMETTO, SENENOA REPENS Pharmaprint, Inc. (US) 2000-11-02 EP disclosed
US-6039950-A SAW PALMETTO PLANT EXTRACTION WITH ALCOHOL, MEASURING FATTY ACID CONTENT, DISTILLATION, DETECTION OF LINOLEIC ACID, ETHYL ESTER AND ETHYL LAURATE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2000-03-21 US disclosed
WO-1999021009-A9 PHARMACEUTICAL GRADE SAW PALMETTO, SERENOA REPENS PHARMAPRINT INC (US) 1999-07-01 WO disclosed
WO-1999021009-A1 PHARMACEUTICAL GRADE SAW PALMETTO, SERENOA REPENS PHARMAPRINT, INC. (US) 1999-04-29 WO disclosed
EP-0337621-B1 PROCESS FOR THE PRODUCTION OF FRUIT PRODUCTS THE HORTICULTURE AND FOOD RESEARCH INSTITUTE OF NEW ZEALAND LIMITED (NZ) 1993-06-23 EP disclosed
US-5202140-A Stabilizing color in kiwi fruit and product HER MAJESTY THE QUEEN IN RIGHT OF NEW ZEALAND FOR DEPARTMENT OF SCIENTIFIC AND INDUSTRIAL RESEARCH, DIVISION OF HORTICULTURE AND PROCESSING (NZ) 1993-04-13 US disclosed
EP-0337621-A1 Process for the production of fruit products THE HORTICULTURE AND FOOD RESEARCH INSTITUTE OF NEW ZEALAND LIMITED (NZ) 1989-10-18 EP disclosed
US-4147625-A Method for clarifying discolored trimethylhydroquinone solutions CONTINENTAL OIL COMPANY (US) 1979-04-03 US disclosed