Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1255653 | 1.00 | CYP2D6 (0.67) | CYP2D6KCNH2 | |
| SCHEMBL1257877 | 0.87 | CYP2D6 (0.73) | CYP2D6KCNH2 | |
| SCHEMBL1257875 | 0.87 | CYP2D6 (0.73) | CYP2D6KCNH2 | |
| SCHEMBL3924795 | 0.82 | CYP2D6 (0.81) | CYP2D6KCNH2 | |
| SCHEMBL3924801 | 0.82 | CYP2D6 (0.81) | CYP2D6KCNH2 | |
| SCHEMBL1255656 | 0.81 | CYP2D6 (0.48) | CYP2D6KCNH2 | |
| SCHEMBL3933779 | 0.81 | CYP2D6 (0.48) | CYP2D6KCNH2 | |
| SCHEMBL1258238 | 0.78 | CYP2D6 (0.58) | CYP2D6KCNH2 | |
| SCHEMBL3437179 | 0.78 | CYP2D6 (0.62) | CYP2D6KCNH2 | |
| SCHEMBL1258241 | 0.78 | CYP2D6 (0.58) | CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879911-B2 | 2-(4-Fluorophenoxy-N-hydroxyacetamide where the \"oxy\" can also be sulfonyl, sulfamyl or sulfinyl; enzyme inhibitors of the \"lethal factor\" enzyme released by bacillus anthraci that splits an essential peptide needed by mammals for signal transmission; antidotes; biological warfare | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-02-01 | — | — | US | disclosed |
| US-20080188565-A1 | Hydroxamic acid derivatives of phenoxy-acetic acids and analogs useful as therapeutic agents for treating anthrax poisoning | PANTHERA BIOPHARMA, LLC | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188565-A1 | Hydroxamic acid derivatives of phenoxy-acetic acids and analogs useful as therapeutic agents for treating anthrax poisoning | ANTXR2, HAAO, PAOX | CYP2D6 1567/4885KCNH2 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.