SCHEMBL12556935

SCHEMBL12556935

O=c1c2cc(O)c(N=Nc3ccc(-c4nnc(-c5ccc(N=Nc6c(O)cc7c(=O)n8c9ccccc9nc8c8cccc6c78)cc5)o4)cc3)c3cccc(c32)c2nc3ccccc3n12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.48
▸ MAPT P10636 4/20 0.48
▸ MEN1 O00255 3/20 0.48
▸ CAMKK1 Q8N5S9 2/20 0.48
▸ CAMKK2 Q96RR4 2/20 0.48
▸ CYP1A2 P05177 2/20 0.48
▸ CYP2D6 P10635 1/20 0.48
▸ CYP2C9 P11712 1/20 0.48
▸ CASP1 P29466 1/20 0.48
▸ CYP2C19 P33261 1/20 0.48
▸ CASP7 P55210 1/20 0.48
▸ CSNK2A2 P19784 1/20 0.46
▸ CSNK2B P67870 1/20 0.46
▸ CSNK2A1 P68400 1/20 0.46
▸ PIM3 Q86V86 1/20 0.46
▸ DYRK2 Q92630 1/20 0.46
▸ MKNK1 Q9BUB5 1/20 0.46
▸ PIM2 Q9P1W9 1/20 0.46
▸ SMN1; SMN2 Q16637 3/20 0.44
▸ POLB P06746 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11911557 0.96 KMT2A (0.48) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL17059538 0.90 KMT2A (0.40) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL12656330 0.88 KMT2A (0.38) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL12556944 0.87 NQO2 (0.46) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL13416009 0.86 KMT2A (0.49) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL10028893 0.85 CAMKK1 (0.44) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL14010228 0.85 KMT2A (0.50) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL10062398 0.84 CAMKK1 (0.43) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL11911553 0.84 NQO2 (0.46) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL11911556 0.82 KMT2A (0.39) KMT2AMAPTMEN1CAMKK1CAMKK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8906586-B2 Coating fluid for photosensitive-layer formation, process for producing the same, photoreceptor produced with the coating fluid, image-forming apparatus employing the photoreceptor, and electrophotographic cartridge employing the photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2014-12-09 — — US disclosed
US-8906586-B2 Coating fluid for photosensitive-layer formation, process for producing the same, photoreceptor produced with the coating fluid, image-forming apparatus employing the photoreceptor, and electrophotographic cartridge employing the photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2014-12-09 — — US disclosed
US-8632931-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-01-21 — — US disclosed
US-8632931-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2014-01-21 — — US disclosed
US-8530123-B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image-forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2013-09-10 — — US disclosed
US-8524429-B2 — — 2013-09-03 — — US disclosed
US-8524429-B2 — — 2013-09-03 — — US disclosed
US-8450032-B2 — — 2013-05-28 — — US disclosed
US-8450032-B2 — — 2013-05-28 — — US disclosed
US-8288066-B2 Electroconductive support with a photosensitive layer of an arylamine-based compound; high sensitivity, chargeability, residual potential, light resistance MITSUBISHI CHEMICAL CORPORATION (JP) 2012-10-16 — — US disclosed
US-20090324282-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-12-31 — — US disclosed
US-7585604-B2 Electrographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2009-09-08 — — US disclosed
US-7585604-B2 Electrographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2009-09-08 — — US disclosed
US-20090202274-A1 COATING FLUID FOR PHOTOSENSITIVE-LAYER FORMATION, PROCESS FOR PRODUCING THE SAME, PHOTORECEPTOR PRODUCED WITH THE COATING FLUID, IMAGE-FORMING APPARATUS EMPLOYING THE PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC CARTRIDGE EMPLOYING THE PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-08-13 — — US disclosed
US-20090202274-A1 COATING FLUID FOR PHOTOSENSITIVE-LAYER FORMATION, PROCESS FOR PRODUCING THE SAME, PHOTORECEPTOR PRODUCED WITH THE COATING FLUID, IMAGE-FORMING APPARATUS EMPLOYING THE PHOTORECEPTOR, AND ELECTROPHOTOGRAPHIC CARTRIDGE EMPLOYING THE PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-08-13 — — US disclosed
US-20080193867-A1 Electrophotographic Photoreceptor and Image-Forming Apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2008-08-14 — — US disclosed
US-20080193867-A1 Electrophotographic Photoreceptor and Image-Forming Apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2008-08-14 — — US disclosed
US-20080050664-A1 Electrographic Photosensitive Member, Process Cartridge and Electrophotographic Apparatus CANON KABUSHIKI KAISHA (JP) 2008-02-28 — — US disclosed
US-20080050664-A1 Electrographic Photosensitive Member, Process Cartridge and Electrophotographic Apparatus CANON KABUSHIKI KAISHA (JP) 2008-02-28 — — US disclosed
EP-0977087-B1 Electrophotographic apparatus CANON KK (JP) 2007-12-12 — — EP disclosed
Send feedback