SCHEMBL1255875

SCHEMBL1255875

CC(C)=NN.NNc1ccncc1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 13/20 0.49
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
KDM6B O15054 5/20 0.45
KDM4D Q6B0I6 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 2/20 0.45
KDM4A O75164 2/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
THRB P10828 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
SIRT3 Q9NTG7 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL2032550 0.90 KDM4C (0.54) KDM4CCA12CA1CA2CA9
Acetone SCHEMBL15923153 0.89 KDM4C (0.53) KDM4CCA12CA1CA2CA9
SCHEMBL19611328 0.88 KDM4C (0.55) KDM4CCA12CA1CA2CA9
SCHEMBL188821 0.88 KDM4C (0.55) KDM4CCA12CA1CA2CA9
Succinimide SCHEMBL27757714 0.79 KDM4C (0.43) KDM4CCA12CA1CA2CA9
SCHEMBL3823398 0.78 KDM4C (0.76) KDM4CKDM6BKDM4DTDP1MEN1
SCHEMBL4429003 0.77 KDM4C (0.54) KDM4CKDM6BKDM4DTDP1MEN1
SCHEMBL31620734 0.77 KDM4C (0.54) KDM4CKDM6BKDM4DTDP1MEN1
Acetone SCHEMBL5667714 0.77 SIRT3 (0.58) KDM4CCA12CA1CA2CA9
SCHEMBL12830011 0.76 KDM4C (0.68) KDM4CKDM6BKDM4DTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7888316-B2 Polypeptide films and methods ARTIFICIAL CELL TECHNOLOGIES, INC. (US) 2011-02-15 US disclosed
US-20100247633-A1 Polypeptide Films and Methods ARTIFICIAL CELL TECHNOLOGIES, INC. (US) 2010-09-30 US disclosed
US-7723294-B2 Polypeptide films and methods ARTIFICIAL CELL TECHNOLOGIES, INC. (US) 2010-05-25 US disclosed
US-20080241228-A1 Polypeptide Films and Methods ARTIFICIAL CELL TECHNOLOGIES, INC. (US) 2008-10-02 US disclosed