SCHEMBL1255890

SCHEMBL1255890

O=C(Oc1ccccc1)C(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.47
CES1 P23141 2/20 0.46
MAOB P27338 1/20 0.46
ATM Q13315 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALDH1A1 P00352 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
NSD2 O96028 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10946374 0.98 ELANE (0.46) ELANECES1MAOBATML3MBTL1
SCHEMBL29281053 0.90 ELANE (0.51) ELANEMAOBATML3MBTL1ALDH1A1
Trifluoroacetic Acid SCHEMBL11498996 0.90 ELANE (0.41) ELANECES1MAOBATML3MBTL1
SCHEMBL9543659 0.88 HDAC1 (0.50) ELANETDP1HDAC1HDAC2KDM4E
SCHEMBL29281054 0.86 POLB (0.49) CES1ATML3MBTL1TDP1HPGD
SCHEMBL544447 0.84 MAOB (0.49) ELANECES1MAOBATML3MBTL1
SCHEMBL4658587 0.83 AKR1C3 (0.51) MAOBHDAC1HDAC2HSD17B10ALDH1A1
SCHEMBL25694687 0.83 ELANE (0.42) ELANECES1MAOBL3MBTL1TDP1
SCHEMBL31257827 0.83 ELANE (0.44) ELANECES1MAOBATML3MBTL1
SCHEMBL21235982 0.83 ELANE (0.53) ELANEMAOBATML3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250144226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2025-05-08 US claimed
CN-119742387-A Full-temperature-range lithium-manganese dioxide soft-package battery electrolyte and battery obtained by same 惠州市惠德瑞锂电科技股份有限公司 2025-04-01 CN claimed
CN-115842112-B Secondary battery, battery module, battery pack and power utilization device thereof 宁德时代新能源科技股份有限公司 2025-01-03 CN claimed
CN-118315657-A Gel electrolyte, preparation method thereof and energy storage device 深圳市合壹新能技术有限公司 2024-07-09 CN claimed
CN-113903993-B Lithium metal battery electrolyte additive, electrolyte and battery thereof 中国科学院大学 2024-04-09 CN claimed
CN-115832180-B Secondary battery, battery module, battery pack and power utilization device thereof 宁德时代新能源科技股份有限公司 2024-03-22 CN claimed
WO-2023130888-A1 SECONDARY BATTERY, BATTERY MODULE, BATTERY PACK AND ELECTRIC DEVICE THEREOF 宁德时代新能源科技股份有限公司 2023-07-13 WO claimed
WO-2023130887-A1 SECONDARY BATTERY, BATTERY MODULE, BATTERY PACK AND ELECTRIC DEVICE THEREOF 宁德时代新能源科技股份有限公司 2023-07-13 WO claimed
CN-115842112-A Secondary battery, battery module, battery pack, and electric device using the same 宁德时代新能源科技股份有限公司 2023-03-24 CN claimed
CN-115832180-A Secondary battery, battery module, battery pack, and electric device using the same 宁德时代新能源科技股份有限公司 2023-03-21 CN claimed
EP-2468708-A1 Catalytic decarboxylative cross-ketonisation of aryl- and alkylcarboxylic acids using iron catalysts Cognis IP Management GmbH (DE) 2012-06-27 EP claimed
US-7935530-B2 Selectively bind DNA and entering nucleus of cells; for modulating gene expression in cells CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2011-05-03 US claimed
US-20080269138-A1 Polyamides with tail structures CALIFORNIA INSTITUTE OF TECHNOLOGY 2008-10-30 US claimed
WO-2008066890-A2 POLYAMIDES WITH TAIL STRUCTURES CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2008-06-05 WO claimed
CN-1856461-A Cycloalkylene compounds as estrogen receptor modulators SMITHKLINE BEECHAM CORP (US) 2006-11-01 CN claimed
EP-1521757-A1 NOVEL TRICYCLIC SPIROPIPERIDINES OR SPIROPYRROLIDINES AstraZeneca AB (SE) 2005-04-13 EP claimed
WO-2004005295-A1 NOVEL TRICYCLIC SPIROPIPERIDINES OR SPIROPYRROLIDINES ASTRAZENECA AB (SE) 2004-01-15 WO claimed
WO-2001014083-A1 AMINE CURABLE FOUNDRY BINDER CONTAINING AN ESTER OF CERTAIN ORGANIC ACIDS ASHLAND INC. (US) 2001-03-01 WO claimed
US-4395521-A Process for curing thermoset resins using phenyl esters of carboxylic acids as latent catalysts UNION CARBIDE CORPORATION (US) 1983-07-26 US claimed
US-4297485-A Production of a selectively protected N-acylated derivative of an aminoglycosidic antibiotic ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1981-10-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269138-A1 Polyamides with tail structures HNRNPH3, PCNA, DNAH12 ELANE 1540/4885CES1 2405/4885MAOB 3873/4885
US-20250144226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE CLN6, CACYBP, CREBBP ELANE 2043/4885CES1 1003/4885MAOB 1361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.