Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.85 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.65 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.65 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.65 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL834686 | 0.92 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL834687 | 0.92 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL833748 | 0.83 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL833749 | 0.83 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL832634 | 0.80 | HDAC1 (0.79) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL832635 | 0.80 | HDAC1 (0.79) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL831605 | 0.79 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL831604 | 0.79 | HDAC1 (1.00) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL831475 | 0.76 | HDAC1 (0.82) | HDAC1HDAC8HDAC3HDAC4HDAC2 | |
| SCHEMBL831474 | 0.76 | HDAC1 (0.82) | HDAC1HDAC8HDAC3HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937650-B1 | HETEROCYCLIC COMPOUNDS | S BIO PTE LTD (SG) | 2011-06-15 | — | — | EP | disclosed |