Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1948090 | 0.91 | PTGDR2 (0.61) | PTGDR2MTORPPARDNR2F2RAB9A | |
| SCHEMBL1950917 | 0.86 | PTGDR2 (0.54) | PTGDR2PPARDCYP11B1CYP11B2NR2F2 | |
| SCHEMBL1949600 | 0.85 | PTGDR2 (0.56) | PTGDR2MTORPPARD | |
| SCHEMBL12542896 | 0.85 | PTGDR2 (0.52) | PTGDR2PPARDCYP11B1CYP11B2PPARG | |
| SCHEMBL1949604 | 0.81 | PTGDR2 (0.60) | PTGDR2 | |
| SCHEMBL1947830 | 0.80 | PTGDR2 (0.55) | PTGDR2PPARD | |
| SCHEMBL1690282 | 0.79 | PTGDR2 (0.77) | PTGDR2CYP11B1CYP11B2 | |
| SCHEMBL1947876 | 0.79 | PTGDR2 (0.64) | PTGDR2PPARDNR2F2RAB9A | |
| SCHEMBL1950749 | 0.78 | PTGDR2 (0.62) | PTGDR2PPARD | |
| SCHEMBL1948039 | 0.78 | PTGDR2 (0.57) | PTGDR2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136877-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2011-06-09 | — | — | US | disclosed |
| WO-2009089192-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | LIGAND PHARMACEUTICALS INC. (US) | 2009-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136877-A1 | 2-PHENYL PHENOXYACETIC ACIDS USEFUL FOR TREATING INFLAMMATORY DISORDERS | HCAR2, PAH, PTGES2 | PTGDR2 15/4885LRRK2 4161/4885MTOR 3028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.