Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 14/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12551248 | 0.91 | KIT (0.51) | KITGPR55MAPK1ACACB | |
| SCHEMBL12572232 | 0.84 | KIT (0.44) | KITACACB | |
| SCHEMBL12551042 | 0.83 | KIT (0.49) | KITGPR55MAPK1ACACB | |
| SCHEMBL256333 | 0.82 | ACACB (0.57) | KITACACB | |
| SCHEMBL16622564 | 0.82 | KIT (0.55) | KITGPR55 | |
| SCHEMBL12551291 | 0.78 | KIT (0.46) | KITACACB | |
| SCHEMBL1953920 | 0.77 | KIT (0.45) | KITACACB | |
| SCHEMBL14754780 | 0.77 | KIT (0.45) | KITACACB | |
| SCHEMBL12550473 | 0.77 | ACACB (0.53) | ACACB | |
| SCHEMBL12572042 | 0.77 | POLB (0.53) | KITACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067306-A1 | CYCLOHEXANE DERIVATIVES AS INHIBITORS OF ACETYL-COA CARBOXYLASE (ACC) | NOVARTIS AG (CH) | 2011-06-09 | — | — | WO | disclosed |