Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 18/20 | 0.84 |
| ▸ | CXCR1 | P25024 | 10/20 | 0.84 |
| ▸ | CCR6 | P51684 | 2/20 | 0.66 |
| ▸ | CCR7 | P32248 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12576507 | 1.00 | CXCR2 (0.84) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL248295 | 0.91 | CXCR2 (1.00) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL12262239 | 0.91 | CXCR2 (1.00) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL12086787 | 0.91 | CXCR2 (1.00) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL12262243 | 0.90 | CXCR2 (0.82) | CXCR2CXCR1CCR6 | |
| SCHEMBL12262246 | 0.90 | CXCR2 (0.82) | CXCR2CXCR1CCR6 | |
| SCHEMBL13591138 | 0.89 | CXCR2 (0.79) | CXCR2CXCR1CCR6 | |
| SCHEMBL12262102 | 0.88 | CXCR2 (0.66) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL12262224 | 0.88 | CXCR2 (0.82) | CXCR2CXCR1CCR6CCR7 | |
| SCHEMBL12576506 | 0.86 | CXCR2 (0.85) | CXCR2CXCR1CCR6CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7964646-B2 | 3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2011-06-21 | — | — | US | disclosed |