Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.66 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.66 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12581993 | 0.84 | S1PR1 (0.66) | S1PR1S1PR3S1PR5 | |
| SCHEMBL27669733 | 0.84 | S1PR1 (0.78) | S1PR1S1PR3S1PR5 | |
| SCHEMBL4562427 | 0.81 | S1PR1 (0.68) | S1PR1S1PR3S1PR5 | |
| SCHEMBL12391707 | 0.81 | S1PR1 (0.60) | S1PR1S1PR3S1PR5KCNH2 | |
| SCHEMBL4043562 | 0.80 | S1PR1 (1.00) | S1PR1S1PR3S1PR5 | |
| SCHEMBL12450020 | 0.80 | S1PR1 (0.58) | S1PR1S1PR3S1PR5KCNH2 | |
| SCHEMBL2006438 | 0.79 | S1PR1 (0.57) | S1PR1S1PR3S1PR5KCNH2 | |
| SCHEMBL2138081 | 0.79 | S1PR1 (0.56) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2133989 | 0.78 | S1PR1 (0.58) | S1PR1S1PR3S1PR5 | |
| SCHEMBL12581668 | 0.77 | S1PR1 (0.55) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011071570-A1 | NOVEL OXADIAZOLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-16 | — | — | WO | disclosed |