Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.57 |
| ▸ | S1PR4 | O95977 | 9/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 9/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TPH1 | P17752 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1312218 | 0.88 | S1PR1 (0.57) | S1PR1S1PR4S1PR5S1PR3NPC1 | |
| SCHEMBL3100041 | 0.86 | S1PR1 (0.56) | S1PR1S1PR4S1PR5S1PR3NPC1 | |
| SCHEMBL3455754 | 0.85 | S1PR1 (0.59) | S1PR1S1PR4S1PR5S1PR3NPC1 | |
| SCHEMBL449651 | 0.85 | S1PR1 (0.59) | S1PR1S1PR4S1PR5S1PR3NPC1 | |
| SCHEMBL1965935 | 0.85 | S1PR1 (0.64) | S1PR1S1PR4S1PR5S1PR3NPC1 | |
| SCHEMBL29151659 | 0.85 | S1PR1 (0.59) | S1PR1S1PR4S1PR5S1PR3NPC1 | |
| SCHEMBL29936941 | 0.83 | NPC1 (0.72) | S1PR1S1PR3ACHENPC1ALDH1A1 | |
| SCHEMBL4742811 | 0.83 | S1PR1 (0.59) | S1PR1S1PR4S1PR5S1PR3NPC1 | |
| SCHEMBL3095950 | 0.82 | S1PR1 (0.61) | S1PR1S1PR4S1PR5S1PR3NPC1 | |
| SCHEMBL3456664 | 0.82 | S1PR1 (0.56) | S1PR1S1PR4S1PR5S1PR3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011071570-A1 | NOVEL OXADIAZOLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-16 | — | — | WO | disclosed |