Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.57 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | CDK16 | Q00536 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12582502 | 0.84 | GSK3B (0.54) | GSK3BDYRK1ACDK2CDK16 | |
| SCHEMBL12583332 | 0.84 | GSK3B (0.49) | GSK3BDYRK1A | |
| SCHEMBL12044000 | 0.83 | GSK3B (0.53) | GSK3BDYRK1ACDK2CDK16 | |
| SCHEMBL15197726 | 0.83 | GSK3B (0.53) | GSK3BDYRK1ACDK2CDK16 | |
| SCHEMBL1964261 | 0.83 | GSK3B (0.53) | GSK3BDYRK1ACDK2CDK16 | |
| SCHEMBL13513573 | 0.82 | GSK3B (0.47) | GSK3BDYRK1ACDK2CDK16 | |
| SCHEMBL15210880 | 0.80 | GSK3B (0.78) | GSK3BDYRK1ACDK2CDK16 | |
| Hydrochloric Acid SCHEMBL15210531 | 0.79 | GSK3B (0.76) | GSK3BDYRK1ACDK2CDK16 | |
| SCHEMBL4791019 | 0.78 | KDM4E (0.57) | GSK3BCDK2 | |
| SCHEMBL30648568 | 0.78 | KDM4E (0.57) | GSK3BCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336128-A1 | Benzoisothiazoles and preparation and uses thereof | Memory Pharmaceuticals Corporation (US) | 2011-06-22 | — | — | EP | disclosed |