SCHEMBL1258640

SCHEMBL1258640

Cc1nc(O)nc(O)c1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1585949 0.84
SCHEMBL4266121 0.84
Thymine SCHEMBL8071134 0.81
SCHEMBL11507948 0.77 MB (0.31)
SCHEMBL9003122 0.77 EGLN1 (0.31)
SCHEMBL16389482 0.73
SCHEMBL7037128 0.72
SCHEMBL12845764 0.72
SCHEMBL1164122 0.72
SCHEMBL10966104 0.72 MEN1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7652128-B2 Toner composition XEROX CORPORATION (US) 2010-01-26 US claimed
US-20060100300-A1 Toner composition XEROX CORPORATION 2006-05-11 US claimed
US-6846525-B2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 2005-01-25 US claimed
US-20040202825-A1 RECORDING SHEETS CONTAINING PURINE, PYRIMIDINE, BENZIMIDAZOLE, IMIDAZOLIDINE, URAZOLE, PYRAZOLE, TRIAZOLE, BENZOTRIAZOLE, TETRAZOLE, AND PYRAZINE COMPOUNDS XEROX CORPORATION 2004-10-14 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0643088-B1 Amino functional polyesters XEROX CORP (US) 2000-07-12 EP claimed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 EP claimed
US-6027844-A SINGLE LAYER POSITIVE ORGANIC PHOTOCONDUCTOR COMPRISING A COMPOSITE COMPRISING AT LEAST ONE PHOTOCONDUCTIVE PHTHALOCYANINE PIGMENT HAVING A PARTICLE SIZE LESS THAN ABOUT 1 MUM UNIFORMLY DISPERSED IN A POLYMERIC BINDER HEWLETT-PACKARD COMPANY (US) 2000-02-22 US claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
EP-0643088-A1 Amino functional polyesters XEROX CORPORATION (US) 1995-03-15 EP claimed
US-5354840-A Functional-amine polyesters XEROX CORPORATION (US) 1994-10-11 US claimed
CN-107759562-B Preparation method of loflupridine hydrochloride 常州四药制药有限公司 2020-10-23 CN disclosed
CN-105669642-B Preparation method of loflupridine hydrochloride 江苏天士力帝益药业有限公司 2020-06-09 CN disclosed
US-9981917-B2 Preparation method for revaprazan hydrochloride JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) 2018-05-29 US disclosed
US-9981917-B2 Preparation method for revaprazan hydrochloride JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) 2018-05-29 US disclosed
US-9981917-B2 Preparation method for revaprazan hydrochloride JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) 2018-05-29 US disclosed
CN-107759562-A A kind of preparation method of hydrochloric acid revaprzan 常州四药制药有限公司 2018-03-06 CN disclosed
US-20170267646-A1 PREPARATION METHOD FOR REVAPRAZAN HYDROCHLORIDE JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) 2017-09-21 US disclosed
US-20170267646-A1 PREPARATION METHOD FOR REVAPRAZAN HYDROCHLORIDE JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) 2017-09-21 US disclosed
US-20170267646-A1 PREPARATION METHOD FOR REVAPRAZAN HYDROCHLORIDE JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) 2017-09-21 US disclosed
WO-2016200840-A1 MONO AND BICYCLIC RING BORONIC ACID, ESTER AND SALT COMPOUNDS AS INHIBITORS OF P97 COMPLEX CLEAVE BIOSCIENCES, INC. (US) 2016-12-15 WO disclosed
CN-105669642-A Revaprzan hydrochloride preparation method 江苏天士力帝益药业有限公司 2016-06-15 CN disclosed
WO-2016078542-A1 PREPARATION METHOD FOR REVAPRAZAN HYDROCHLORIDE 江苏天士力帝益药业有限公司 2016-05-26 WO disclosed
US-20130224624-A1 PROTON EXCHANGE MEMBRANES RENO (US) 2013-08-29 US disclosed
CN-1770022-B Toner composition XEROX CORP 2012-05-02 CN disclosed
US-8044068-B2 Aminopyrrolidine compound TAISHO PHARMACEUTICAL CO., LTD (JP) 2011-10-25 US disclosed
US-20110033776-A1 PROTON EXCHANGE MEMBRANES Board of regents of the Nevada System of Higher Education, on Behalf of the University of 2011-02-10 US disclosed
US-7652128-B2 Toner composition XEROX CORPORATION (US) 2010-01-26 US disclosed
EP-1655323-B1 Toner composition XEROX CORP (US) 2010-01-20 EP disclosed
US-20090291940-A1 AMINOPYRROLIDINE COMPOUND TAISHO PHARMACEUTICAL CO., LTD. (JP) 2009-11-26 US disclosed
CN-100381936-C Linked dihydrazone-based charge transport compounds SAMSUNG ELECTRONICS CO LTD (KR) 2008-04-16 CN disclosed
EP-1519235-B1 Linked dihydrazone-based charge transport compounds SAMSUNG ELECTRONICS CO LTD (KR) 2007-07-11 EP disclosed
US-7074532-B2 Linked dihydrazone-based charge transport compounds SAMSUNG ELECTRONICS, CO., LTD. (KR) 2006-07-11 US disclosed
US-20060100300-A1 Toner composition XEROX CORPORATION 2006-05-11 US disclosed
EP-1655323-A2 Toner composition Xerox Corporation (US) 2006-05-10 EP disclosed
CN-1770022-A Toner composition XEROX CORP (US) 2006-05-10 CN disclosed
US-20050197350-A1 Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof TAISHO PHARMACEUTICAL CO., LTD. 2005-09-08 US disclosed
EP-1519235-A2 Linked dihydrazone-based charge transport compounds Samsung Electronics Co., Ltd. (KR) 2005-03-30 EP disclosed
CN-1598699-A Linked dihydrazone-based charge transport compounds SAMSUNG ELECTRONICS CO LTD (KR) 2005-03-23 CN disclosed
US-20050058916-A1 Linked dihydrazone-based charge transport compounds S-PRINTING SOLUTION CO., LTD. (KR) 2005-03-17 US disclosed
US-6846525-B2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 2005-01-25 US disclosed
WO-2004087669-A1 NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF TAISHO PHARMACEUTICAL CO. LTD. (JP) 2004-10-14 WO disclosed
US-20040202825-A1 RECORDING SHEETS CONTAINING PURINE, PYRIMIDINE, BENZIMIDAZOLE, IMIDAZOLIDINE, URAZOLE, PYRAZOLE, TRIAZOLE, BENZOTRIAZOLE, TETRAZOLE, AND PYRAZINE COMPOUNDS XEROX CORPORATION 2004-10-14 US disclosed
EP-1464335-A2 Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist Taisho Pharmaceutical Co. Ltd. (JP) 2004-10-06 EP disclosed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP disclosed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP disclosed
EP-0643088-B1 Amino functional polyesters XEROX CORP (US) 2000-07-12 EP disclosed
EP-0673783-B1 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORP (US) 2000-07-05 EP disclosed
US-6027844-A SINGLE LAYER POSITIVE ORGANIC PHOTOCONDUCTOR COMPRISING A COMPOSITE COMPRISING AT LEAST ONE PHOTOCONDUCTIVE PHTHALOCYANINE PIGMENT HAVING A PARTICLE SIZE LESS THAN ABOUT 1 MUM UNIFORMLY DISPERSED IN A POLYMERIC BINDER HEWLETT-PACKARD COMPANY (US) 2000-02-22 US disclosed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US disclosed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO disclosed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO disclosed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US disclosed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US disclosed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US disclosed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP disclosed
EP-0643088-A1 Amino functional polyesters XEROX CORPORATION (US) 1995-03-15 EP disclosed
US-5354840-A Functional-amine polyesters XEROX CORPORATION (US) 1994-10-11 US disclosed
US-5128429-A Low temperature block polymerization without randomization RAYCHEM LIMITED (GB) 1992-07-07 US disclosed
EP-0154506-B1 PREPARATION OF ORGANIC POLYMERS RAYCHEM LIMITED (GB) 1992-02-05 EP disclosed
US-4999411-A Polythioethers, polythiocarbonates, polythioamides, polythioimides RAYCHEM LIMITED (GB) 1991-03-12 US disclosed
US-4960835-A ENGINEERING THERMOPLASTICS RAYCHEM LIMITED (GB) 1990-10-02 US disclosed
US-4845179-A CONDENSATION POLYMERIZATION RAYCHEM LIMITED (GB) 1989-07-04 US disclosed
EP-0126394-B1 ENZYMATIC REMOVAL OF AROMATIC HYDROXY COMPOUNDS AND AROMATIC AMINES FROM WASTE WATERS PHILLIPS PETROLEUM COMPANY (US) 1987-10-28 EP disclosed
EP-0154506-A2 Preparation of organic polymers RAYCHEM LIMITED (GB) 1985-09-11 EP disclosed
EP-0126394-A1 Enzymatic removal of aromatic hydroxy compounds and aromatic amines from waste waters PHILLIPS PETROLEUM COMPANY (US) 1984-11-28 EP disclosed
US-4485016-A Enzymatic removal of aromatic hydroxy compounds and aromatic amines from waste waters PHILLIPS PETROLEUM COMPANY (US) 1984-11-27 US disclosed
US-4485016-A Enzymatic removal of aromatic hydroxy compounds and aromatic amines from waste waters PHILLIPS PETROLEUM COMPANY (US) 1984-11-27 US disclosed