SCHEMBL12587567

SCHEMBL12587567

CCCCCCc1cc(-c2ccc(-c3ccc(-c4ccc(-c5cc(CCCCCC)c(C)s5)c5nsnc45)s3)c3nsnc23)sc1C

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TYR P14679 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ TP53 P04637 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ ALOX5 P09917 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ GPR3 P46089 1/20 0.32
▸ LIPG Q9Y5X9 1/20 0.31
▸ ELANE P08246 1/20 0.30
▸ CTSG P08311 1/20 0.30
▸ CHRM1 P11229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12587577 0.96 TYR (0.31) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL12593277 0.96 TYR (0.35) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL862401 0.96 TYR (0.35) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL12587579 0.95 MEN1 (0.30) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL12610408 0.91 TYR (0.32) TYRTP53
SCHEMBL16285008 0.90 TYR (0.34) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL12610389 0.90 TYR (0.31) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL15724568 0.90 TYR (0.31) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL12610358 0.90 TYR (0.31) TYRMEN1TP53CYP3A4ALOX5
SCHEMBL12587568 0.89 TYR (0.31) TYRMEN1TP53CYP3A4ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110156018-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110156018-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME CCNL2, ARL1, RIF1 TYR 2118/4885MEN1 3200/4885TP53 4746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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