Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12592473 | 0.88 | BACE1 (0.50) | BACE1CTSD | |
| SCHEMBL12592509 | 0.86 | BACE1 (0.52) | BACE1CTSD | |
| SCHEMBL12592211 | 0.85 | BACE1 (0.56) | BACE1CTSD | |
| SCHEMBL12592507 | 0.83 | BACE1 (0.46) | BACE1CTSD | |
| SCHEMBL12592322 | 0.78 | BACE1 (0.49) | BACE1CTSD | |
| SCHEMBL12592251 | 0.77 | BACE1 (0.44) | BACE1CTSD | |
| SCHEMBL12592737 | 0.75 | BACE1 (0.44) | BACE1CTSD | |
| SCHEMBL12593092 | 0.74 | BACE1 (0.41) | BACE1CTSD | |
| SCHEMBL447104 | 0.74 | BACE1 (0.59) | BACE1CTSD | |
| SCHEMBL12593094 | 0.74 | BACE1 (0.70) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072064-A1 | S PIRO [CHROMAN - 4, 4 ' - IMIDAZOL] ONES AS BETA - SECRETASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2011-06-16 | — | — | WO | disclosed |