Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513062 | 0.97 | SMN1; SMN2 (0.35) | FPR2SMN1; SMN2KDM4EPKMTYMP | |
| SCHEMBL7515622 | 0.78 | SMN1; SMN2 (0.34) | SMN1; SMN2KDM4EPKMCNR1ELANE | |
| SCHEMBL17551625 | 0.75 | BACE1 (0.40) | — | |
| SCHEMBL13558977 | 0.75 | BACE1 (0.40) | — | |
| SCHEMBL7513872 | 0.74 | SMN1; SMN2 (0.32) | SMN1; SMN2KDM4EPKMTYMP | |
| SCHEMBL8290209 | 0.74 | SMN1; SMN2 (0.35) | SMN1; SMN2TYMPCNR1 | |
| SCHEMBL7524859 | 0.72 | EPHX1 (0.40) | SMN1; SMN2 | |
| SCHEMBL7525031 | 0.71 | EPHX1 (0.42) | — | |
| SCHEMBL4620986 | 0.71 | TYMP (0.37) | KDM4EPKMTYMPCNR1ELANE | |
| SCHEMBL7508906 | 0.71 | SMN1; SMN2 (0.30) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2335701-A1 | Heterocyclic aspartyl protease inhibitors | Schering Corporation (US) | 2011-06-22 | — | — | EP | disclosed |