Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 13/20 | 1.00 |
| ▸ | RPS6KA2 | Q15349 | 9/20 | 0.78 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.60 |
| ▸ | RET | P07949 | 1/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.60 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.60 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
| ▸ | FLT3 | P36888 | 1/20 | 0.60 |
| ▸ | CLK1 | P49759 | 1/20 | 0.60 |
| ▸ | CLK2 | P49760 | 1/20 | 0.60 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.60 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.60 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.60 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14973161 | 1.00 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2PRKD3ADRB2RET | |
| SCHEMBL14972925 | 1.00 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2PRKD3ADRB2RET | |
| SCHEMBL14972924 | 1.00 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2PRKD3ADRB2RET | |
| SCHEMBL14973160 | 1.00 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2PRKD3ADRB2RET | |
| SCHEMBL17772104 | 0.92 | RPS6KA3 (0.86) | RPS6KA3RPS6KA2PRKD3ADRB2RET | |
| SCHEMBL14973127 | 0.89 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2PRKD3ADRB2RET | |
| SCHEMBL12595454 | 0.89 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2PRKD3ADRB2RET | |
| SCHEMBL17772103 | 0.89 | RPS6KA3 (0.80) | RPS6KA3RPS6KA2PRKD3ADRB2RET | |
| SCHEMBL14972988 | 0.88 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2 | |
| SCHEMBL1981999 | 0.88 | RPS6KA3 (1.00) | RPS6KA3RPS6KA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011071725-A1 | HETEROCYCLIC COMPOUNDS CONTAINING A PYRROLOPYRIDINE OR BENZIMIDAZOLE CORE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-06-16 | — | — | WO | disclosed |