Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12600926 | 0.94 | S1PR1 (0.50) | S1PR1S1PR3S1PR5 | |
| SCHEMBL13583076 | 0.89 | S1PR1 (0.60) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1984423 | 0.87 | S1PR1 (0.51) | S1PR1S1PR3S1PR5 | |
| SCHEMBL12601092 | 0.82 | S1PR1 (0.61) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1981508 | 0.81 | S1PR1 (0.51) | S1PR1S1PR3S1PR5 | |
| SCHEMBL12601091 | 0.80 | S1PR1 (0.59) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1993588 | 0.80 | S1PR1 (0.49) | S1PR1S1PR3S1PR5 | |
| SCHEMBL2054381 | 0.77 | S1PR1 (0.48) | S1PR1S1PR3S1PR5MAP4K4MINK1 | |
| SCHEMBL12808935 | 0.76 | S1PR1 (0.59) | S1PR1S1PR3S1PR5MAP4K4MINK1 | |
| Hydrochloric Acid SCHEMBL1398421 | 0.75 | S1PR1 (0.59) | S1PR1S1PR3S1PR5MAP4K4MINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011072488-A1 | OXADIAZOLE SUBSTITUTED INDAZOLE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS | GLAXO GROUP LIMITED (GB) | 2011-06-23 | — | — | WO | disclosed |