Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 7/20 | 0.53 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.37 |
| ▸ | CDC25B | P30305 | 4/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22330637 | 1.00 | SLC5A2 (0.53) | SLC5A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL5522850 | 1.00 | SLC5A2 (0.53) | SLC5A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12425802 | 0.90 | SLC5A2 (0.45) | SLC5A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12425799 | 0.90 | SLC5A2 (0.43) | SLC5A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12425796 | 0.90 | SLC5A2 (0.43) | SLC5A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL147087 | 0.89 | SLC5A2 (0.54) | SLC5A2 | |
| SCHEMBL9973927 | 0.89 | SLC5A2 (0.54) | SLC5A2 | |
| SCHEMBL12425827 | 0.89 | SLC5A2 (0.41) | SLC5A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12425812 | 0.88 | SLC5A2 (0.42) | SLC5A2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL12425817 | 0.88 | SLC5A2 (0.41) | SLC5A2SSTR1SSTR2SSTR4SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7943788-B2 | Including the antidiabetic, antiobesity sodium glucose transport inhibitor Canagliflozin (1-( beta -D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene) | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-05-17 | — | — | US | disclosed |