SCHEMBL126039

SCHEMBL126039

[CH2]c1c(CO)cnc(C)c1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.63
ALDH1A1 P00352 4/20 0.63
HPGD P15428 4/20 0.63
HSD17B10 Q99714 1/20 0.63
PDXK O00764 3/20 0.61
LMNA P02545 4/20 0.58
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
AOX1 Q06278 1/20 0.56
TRIM24 O15164 1/20 0.54
TRIM33 Q9UPN9 1/20 0.54
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
HIF1A Q16665 1/20 0.40
GAA P10253 2/20 0.40
GFER P55789 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3442719 0.81 KDM4E (0.70) KDM4EALDH1A1HPGDHSD17B10PDXK
SCHEMBL1049253 0.79 KDM4E (0.68) KDM4EALDH1A1HPGDHSD17B10PDXK
Hydrochloric Acid SCHEMBL191715 0.78 KDM4E (0.66) KDM4EALDH1A1HPGDHSD17B10PDXK
Hydrochloric Acid SCHEMBL29733341 0.78 KDM4E (0.66) KDM4EALDH1A1HPGDHSD17B10PDXK
Pyridoxine SCHEMBL2322958 0.78 HPGD (1.00) KDM4EALDH1A1HPGDHSD17B10PDXK
Pyridoxine SCHEMBL3506 0.78 HPGD (1.00) KDM4EALDH1A1HPGDHSD17B10PDXK
Pyridoxine SCHEMBL30267871 0.78 HPGD (1.00) KDM4EALDH1A1HPGDHSD17B10PDXK
Pyridoxine SCHEMBL30877002 0.78 HPGD (1.00) KDM4EALDH1A1HPGDHSD17B10PDXK
Pyridoxine SCHEMBL4900587 0.76 HPGD (0.96) KDM4EALDH1A1HPGDHSD17B10PDXK
Pyridoxine SCHEMBL7588196 0.76 KDM4E (0.96) KDM4EALDH1A1HPGDHSD17B10PDXK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230407087-A1 PARTICLES COMPRISING POLYAMIDES WITH PENDENT OPTICAL ABSORBERS AND RELATED METHODS XEROX CORPORATION (US) 2023-12-21 US claimed
US-20230373130-A1 OPTICAL ABSORBING THERMOPLASTIC POLYMER PARTICLES AND METHODS OF PRODUCTION AND USES THEREOF XEROX CORPORATION (US) 2023-11-23 US claimed
US-11801617-B2 Optical absorbing thermoplastic polymer particles and methods of production and uses thereof XEROX CORPORATION (US) 2023-10-31 US claimed
US-11787937-B2 Particles comprising polyamides with pendent optical absorbers and related methods XEROX CORPORATION (US) 2023-10-17 US claimed
CN-110139673-B Use of non-transition metal coordinated pyridoxyl compounds for the prevention and treatment of chemotherapy-induced PSN 卡尔森图纳投资公司 2022-03-22 CN claimed
US-20210069935-A1 OPTICAL ABSORBING THERMOPLASTIC POLYMER PARTICLES AND METHODS OF PRODUCTION AND USES THEREOF XEROX CORPORATION (US) 2021-03-11 US claimed
US-20210070991-A1 PARTICLES COMPRISING POLYAMIDES WITH PENDENT OPTICAL ABSORBERS AND RELATED METHODS XEROX CORPORATION (US) 2021-03-11 US claimed
US-20210070990-A1 PARTICLES COMPRISING POLYAMIDES WITH IN-BACKBONE OPTICAL ABSORBERS AND RELATED METHODS XEROX CORPORATION (US) 2021-03-11 US claimed
EP-3789431-A2 PARTICLES COMPRISING POLYAMIDES WITH IN-BACKBONE OPTICAL ABSORBERS AND RELATED METHODS Xerox Corporation (US) 2021-03-10 EP claimed
EP-3789432-A2 PARTICLES COMPRISING POLYAMIDES WITH PENDENT OPTICAL ABSORBERS AND RELATED METHODS Xerox Corporation (US) 2021-03-10 EP claimed
US-5891468-A DRUG DELIVERY SEQUUS PHARMACEUTICALS, INC. (US) 1999-04-06 US claimed
WO-1999005094-A1 NOVEL COMPOSITIONS FOR THE DELIVERY OF NEGATIVELY CHARGED MOLECULES RIBOZYME PHARMACEUTICALS, INCORPORATED (US) 1999-02-04 WO claimed
WO-1998016202-A2 FUSOGENIC LIPOSOME COMPOSITION AND METHOD SEQUUS PHARMACEUTICALS, INC. (US) 1998-04-23 WO claimed
US-5739121-A CYCLIC OLIGOSACCHARIDES HAVING MONOMERS IN PYRANOSIDE FORM, COMPRISING AT LEAST TWO FLUORINE ATOMS ATTACHED TO CYCLIC OLIGOSACCHARIDE OR SUBSTITUENT UNIVERSITY OF ALBERTA (CA) 1998-04-14 US claimed
EP-0435911-B1 CELL CULTURE MEDIUM FOR ENHANCED CELL GROWTH, CULTURE LONGEVITY AND PRODUCT EXPRESSION CETUS ONCOLOGY CORP (US) 1996-03-13 EP claimed
EP-0297303-B1 Fluorophores for encapsulation into liposomes ABBOTT LAB (US) 1995-03-15 EP claimed
US-4978612-A Coupling of nitrogen heterocyclic compound and aromatic amine; dye forming KONICA CORPORATION (JP) 1990-12-18 US claimed
US-4970074-A FLUORESCEIN DERIVATIVES; DRUG DELIVERY ABBOTT LABORATORIES (US) 1990-11-13 US claimed
US-4912208-A Spiro(phthalan-1,9'-xanthene) ring ABBOTT LABORATORIES (US) 1990-03-27 US claimed
EP-0297303-A2 Fluorophores for encapsulation into liposomes ABBOTT LABORATORIES (US) 1989-01-04 EP claimed