⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128754 | 0.81 | — | — | |
| SCHEMBL28257172 | 0.78 | HCAR2 (0.45) | — | |
| SCHEMBL127082 | 0.77 | — | — | |
| SCHEMBL9019526 | 0.77 | — | — | |
| SCHEMBL2410094 | 0.77 | — | — | |
| SCHEMBL27573884 | 0.77 | — | — | |
| Diethyl Maleate SCHEMBL28432840 | 0.76 | HCAR2 (0.73) | — | |
| SCHEMBL15283301 | 0.75 | HCAR2 (0.52) | — | |
| SCHEMBL293240 | 0.75 | GAA (0.50) | — | |
| Diethyl Maleate SCHEMBL7743777 | 0.75 | HCAR2 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100577658-C | Quinazoline derivatives | ASTRAZENECA AB | 2010-01-06 | — | — | CN | claimed |
| US-20090062497-A1 | Borate Salts, Method for the Production Thereof and Use Thereof | CHEMETALL GMBH (DE) | 2009-03-05 | — | — | US | claimed |
| EP-1934235-A1 | BORATE SALTS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF | Chemetall GmbH (DE) | 2008-06-25 | — | — | EP | claimed |
| WO-2007042500-A1 | BORATE SALTS, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF | CHEMETALL GMBH (DE) | 2007-04-19 | — | — | WO | claimed |
| JP-2007506716-A | — | — | 2007-03-22 | — | — | JP | claimed |
| US-20070043010-A1 | Quinazoline derivatives | ASTRAZENECA UK LIMITED (GB) | 2007-02-22 | — | — | US | claimed |
| CN-1886399-A | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2006-12-27 | — | — | CN | claimed |
| EP-1670786-A1 | QUINAZOLINE DERIVATIVES | Astrazeneca AB (SE) | 2006-06-21 | — | — | EP | claimed |
| WO-2005030757-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-04-07 | — | — | WO | claimed |
| CN-1198742-A | Pyrimidin-4-one derivatives, their use as herbicides, intermediates for their production and process for producing these compounds | SUMITOMO CHEMICAL CO (JP) | 1998-11-11 | — | — | CN | claimed |
| EP-2464623-B1 | THE RING OPENING OF LACTONES AND LACTAMS | NOVARTIS AG (CH) | 2020-11-04 | — | — | EP | disclosed |
| CN-104768980-A | Broad molecular weight distribution polypropylene resins | EXXONMOBIL CHEM PATENTS INC | 2015-07-08 | — | — | CN | disclosed |
| CN-104736627-A | Propylene resin composition for retort pouch-packaging film | SUN ALLOMER LTD | 2015-06-24 | — | — | CN | disclosed |
| CN-104109212-A | Solid catalyst component used for olefin polymerization and catalyst | BEIJING LIHE ZHIXIN TECHNOLOGY CO LTD | 2014-10-22 | — | — | CN | disclosed |
| CN-101522657-B | STAT3/5 activation inhibitor | OTSUKA PHARMACEUTICAL CO.,LTD. (JP) | 2014-10-15 | — | — | CN | disclosed |
| CN-1141036-A | 1,3-Oxazin-4-one derivatives, process and intermediates for their preparation and their use as herbicides | RHONE POULENC AGROCHIMIE CORP (FR) | 1997-01-22 | — | — | CN | disclosed |
| US-5559111-A | HYPOTENSIVE AGENTS; RENIN INHIBITORS; Aliskiren | CIBA-GEIGY CORPORATION (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0716077-A1 | Aromatically substituted omega amino alcanoic acid amides and alcanoic diamides and their use as renine inhibitors | CIBA-GEIGY AG (CH) | 1996-06-12 | — | — | EP | disclosed |
| EP-0678503-A1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | CIBA-GEIGY AG (CH) | 1995-10-25 | — | — | EP | disclosed |
| CN-85106532-A | The preparation of Cephem Derivative | — | 1986-10-01 | — | — | CN | disclosed |