⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267799 | 0.69 | — | — | |
| SCHEMBL3126068 | 0.67 | — | — | |
| SCHEMBL8728820 | 0.65 | — | — | |
| SCHEMBL23546 | 0.64 | — | — | |
| SCHEMBL792741 | 0.63 | — | — | |
| Ammonia Solution, Strong SCHEMBL7121772 | 0.60 | — | — | |
| Methane SCHEMBL28832802 | 0.60 | — | — | |
| SCHEMBL18783524 | 0.60 | — | — | |
| SCHEMBL185771 | 0.60 | — | — | |
| SCHEMBL10458007 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020132824-A1 | Aryl fused azapolycyclic compounds | COE JOTHAM WADSWORTH (US) | 2002-09-19 | — | — | US | claimed |
| US-20020111350-A1 | Aryl fused azapolycyclic compounds | COE JOTHAM WADSWORTH (US) | 2002-08-15 | — | — | US | claimed |
| US-4161476-A | α-Halo-2-oxo-1-azetidinemethane-carboxylic acid compounds | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | claimed |
| EP-3903812-A1 | ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS | Agensys, Inc. (US) | 2021-11-03 | — | — | EP | disclosed |
| EP-3409287-B9 | ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS | AGENSYS INC (US) | 2021-07-21 | — | — | EP | disclosed |
| EP-3409287-B1 | ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS | AGENSYS INC (US) | 2021-04-07 | — | — | EP | disclosed |
| EP-3409287-A1 | ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 191P4D12 PROTEINS | Agensys, Inc. (US) | 2018-12-05 | — | — | EP | disclosed |
| CN-108091826-A | Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same | 三菱化学株式会社 | 2018-05-29 | — | — | CN | disclosed |
| EP-2866783-B1 | SUNSCREEN COMPOSITIONS CONTAINING AN ULTRAVIOLET RADIATION-ABSORBING POLYMER | JOHNSON & JOHNSON CONSUMER INC (US) | 2018-01-10 | — | — | EP | disclosed |
| CN-106848406-A | Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same | 三菱化学株式会社 | 2017-06-13 | — | — | CN | disclosed |
| CN-105633345-A | Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same | MITSUBISHI CHEM CORP | 2016-06-01 | — | — | CN | disclosed |
| EP-2066788-B1 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | CODEXIS INC (US) | 2014-07-23 | — | — | EP | disclosed |
| US-8617864-B2 | Polynucleotides encoding ketoreductases for producing stereoisomerically pure statins and synthetic intermediates therefor | CODEXIS, INC. (US) | 2013-12-31 | — | — | US | disclosed |
| US-20130040364-A1 | POLYNUCLEOTIDES ENCODING KETOREDUCTASES FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | CODEXIS, INC. (US) | 2013-02-14 | — | — | US | disclosed |
| US-8287888-B2 | Thermosensitive polyphosphazene-bioactive molecule conjugates, preparation method thereof and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2012-10-16 | — | — | US | disclosed |
| US-8273547-B2 | Engineered ketoreductases and methods for producing stereoisomerically pure statins | CODEXIS, INC. (US) | 2012-09-25 | — | — | US | disclosed |
| US-20110195465-A1 | Compositions and Methods for Producing Stereoisomerically Pure Statins and Synthetic Intermediates Therefor | CODEXIS, INC. (US) | 2011-08-11 | — | — | US | disclosed |
| US-7879585-B2 | Ketoreductases of Saccharomyces cerevisiae; host cells | CODEXIS, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| US-20090181088-A1 | THERMOSENSITIVE POLYPHOSPHAZENE-BIOACTIVE MOLECULE CONJUGATES, PREPARATION METHOD THEREOF AND USE THEREOF | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-07-16 | — | — | US | disclosed |
| US-20080248539-A1 | COMPOSITIONS AND METHODS FOR PRODUCING STEREOISOMERICALLY PURE STATINS AND SYNTHETIC INTERMEDIATES THEREFOR | CODEXIS, INC. (US) | 2008-10-09 | — | — | US | disclosed |