Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A3 | Q9HAS3 | 3/20 | 0.71 |
| ▸ | TYR | P14679 | 3/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12610400 | 1.00 | SLC28A3 (0.71) | SLC28A3TYRHIF1ASLC5A1ATM | |
| SCHEMBL12610424 | 0.91 | SLC28A3 (0.61) | SLC28A3TYRHIF1ASLC5A1ATM | |
| SCHEMBL166162 | 0.89 | SLC28A3 (0.69) | SLC28A3TYRHIF1ASLC5A1ATM | |
| SCHEMBL3664789 | 0.89 | SLC28A3 (0.69) | SLC28A3TYRHIF1ASLC5A1ATM | |
| SCHEMBL2923796 | 0.89 | SLC28A3 (0.69) | SLC28A3TYRHIF1ASLC5A1ATM | |
| SCHEMBL8657750 | 0.89 | SLC28A3 (0.69) | SLC28A3TYRHIF1ASLC5A1ATM | |
| SCHEMBL7181752 | 0.89 | SLC28A3 (0.69) | SLC28A3TYRHIF1ASLC5A1ATM | |
| SCHEMBL1706261 | 0.89 | SLC28A3 (0.69) | SLC28A3TYRHIF1ASLC5A1ATM | |
| SCHEMBL1315789 | 0.88 | TYR (0.77) | SLC28A3TYRHIF1ASLC5A1SLC5A2 | |
| SCHEMBL3662700 | 0.88 | SLC28A3 (0.68) | SLC28A3TYRHIF1ASLC5A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9707417-B2 | Use of benzotropolone derivatives as UV absorbers and antioxidants and their use in sunscreens and/or cosmetic compositions | BASF SE (DE) | 2017-07-18 | — | — | US | disclosed |
| US-9707417-B2 | Use of benzotropolone derivatives as UV absorbers and antioxidants and their use in sunscreens and/or cosmetic compositions | BASF SE (DE) | 2017-07-18 | — | — | US | disclosed |
| EP-2296760-B1 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | BASF SE (DE) | 2016-03-16 | — | — | EP | disclosed |
| US-20110123468-A1 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | BASF SE (DE) | 2011-05-26 | — | — | US | disclosed |
| US-20110123468-A1 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | BASF SE (DE) | 2011-05-26 | — | — | US | disclosed |
| WO-2009156324-A2 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | BASF SE (DE) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110123468-A1 | USE OF BENZOTROPOLONE DERIVATIVES AS UV ABSORBERS AND ANTIOXIDANTS AND THEIR USE IN SUNSCREENS AND/OR COSMETIC COMPOSITIONS | CBR3, SCO2, CBR1 | SLC28A3 2661/4885TYR 25/4885HIF1A 1709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.