Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 2/20 | 0.43 |
| ▸ | CBX7 | O95931 | 2/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.43 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.43 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203507 | 0.83 | PTPN1 (0.70) | PTPN1CYP3A4DHODHCBX7CDYL | |
| SCHEMBL27870931 | 0.81 | SMN1; SMN2 (0.50) | PTPN1CYP3A4DHODHCBX7CDYL | |
| SCHEMBL2479753 | 0.81 | PTPN1 (0.49) | PTPN1CYP3A4DHODHCBX7CDYL | |
| SCHEMBL1054478 | 0.81 | GSK3B (0.52) | PTPN1CYP3A4DHODHCBX7CDYL | |
| SCHEMBL13566598 | 0.81 | PTPN1 (0.67) | PTPN1CYP3A4CBX7CDYLCDY1; CDY1B | |
| SCHEMBL8751033 | 0.80 | GSK3B (0.64) | NPC1RAB9AGSK3BKDM4EHPGD | |
| SCHEMBL12521014 | 0.79 | PTPN1 (0.46) | PTPN1CYP3A4SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL264367 | 0.79 | CYP2A6 (0.55) | DHODHNPC1ALDH1A1RAB9ACYP2A6 | |
| SCHEMBL30350490 | 0.79 | CYP2A6 (0.55) | DHODHNPC1ALDH1A1RAB9ACYP2A6 | |
| SCHEMBL12647724 | 0.78 | PTPN1 (0.44) | PTPN1CYP3A4SMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152246-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | INTERMUNE, INC. (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152246-A1 | NOVEL INHIBITORS OF HEPATITIS C VIRUS REPLICATION | EIF2AK2, HAVCR2, IRF3 | PTPN1 2999/4885CYP3A4 1292/4885DHODH 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.