SCHEMBL12620552

SCHEMBL12620552

C=CC(=O)OC(CCl)OP(=O)(O)O

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 3/20 0.33
TSHR P16473 5/20 0.32
ALDH1A1 P00352 3/20 0.31
TP53 P04637 2/20 0.31
HIF1A Q16665 2/20 0.31
CYP3A4 P08684 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2024149 0.82 SMPD1 (0.41) SMPD1TSHRALDH1A1TP53HIF1A
SCHEMBL6790640 0.79 SMPD1 (0.46) SMPD1TSHRALDH1A1TP53HIF1A
SCHEMBL28923769 0.78 TSHR (0.30) TSHR
SCHEMBL28151162 0.78 SMPD1 (0.34) SMPD1TSHR
SCHEMBL18544291 0.78 TSHR (0.43) SMPD1TSHRALDH1A1TP53HIF1A
SCHEMBL6791410 0.77 SMPD1 (0.56) SMPD1TSHR
SCHEMBL6783963 0.76 SMPD1 (0.63) SMPD1TSHR
SCHEMBL23581995 0.74 SMPD1 (0.66) SMPD1TSHR
SCHEMBL21541950 0.74 SMPD1 (0.66) SMPD1TSHR
SCHEMBL21541952 0.74 SMPD1 (0.66) SMPD1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7951310-B2 Nanophase carbon black grafted with organic compound in situ EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2011-05-31 US disclosed
US-20070235692-A1 Nanophase carbon black grafted with organic compound in situ, synthesis thereof and articles therefrom EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2007-10-11 US disclosed