Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16170703 | 0.88 | CYP2A6 (0.50) | CYP2A6CYP1A2ALOX5TDP1CA2 | |
| SCHEMBL5610449 | 0.87 | KDM4E (0.58) | CYP2A6CYP1A2KDM4EMAPTBACE1 | |
| SCHEMBL19983484 | 0.86 | IGF1R (0.49) | CYP2A6CYP1A2TDP1CA2IGF1R | |
| SCHEMBL2604704 | 0.83 | CYP2A6 (0.59) | CYP2A6CYP1A2KDM4EMAPTBACE1 | |
| SCHEMBL2311805 | 0.82 | KDM4E (0.54) | CYP2A6CYP1A2KDM4EMAPTBACE1 | |
| SCHEMBL2312808 | 0.82 | KDM4E (0.54) | CYP2A6CYP1A2KDM4EMAPTBACE1 | |
| SCHEMBL3677920 | 0.81 | CYP2A6 (0.56) | CYP2A6CYP1A2TDP1SIGMAR1 | |
| SCHEMBL17025357 | 0.81 | CYP1A2 (0.59) | CYP2A6CYP1A2KDM4EMAPTBACE1 | |
| SCHEMBL15890465 | 0.80 | KDM4E (0.52) | CYP1A2KDM4EMAPTBACE1ALDH1A1 | |
| SCHEMBL79723 | 0.78 | CYP1A2 (0.56) | CYP2A6CYP1A2KDM4EMAPTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9822218-B2 | Process for producing a high molecular-weight aromatic polycarbonate resin | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-11-21 | — | — | US | disclosed |
| EP-2674445-B1 | PROCESS FOR MANUFACTURING BRANCHED AROMATIC POLYCARBONATE RESIN WITH DESIRED DEGREE OF BRANCHING | MITSUBISHI GAS CHEMICAL CO (JP) | 2017-10-11 | — | — | EP | disclosed |
| US-9701788-B2 | Method for producing branched aromatic polycarbonate resin | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-07-11 | — | — | US | disclosed |
| US-20170174833-A1 | HIGH-FLUIDITY POLYCARBONATE COPOLYMER, PROCESS FOR PRODUCTION HIGHLY POLYMERIZED AROMATIC POLYCARBONATE RESIN AND AROMATIC POLYCARBONATE COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2017-06-22 | — | — | US | disclosed |
| US-20160272757-A1 | PROCESS FOR PRODUCING A HIGH MOLECULAR-WEIGHT AROMATIC POLYCARBONATE RESIN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2016-09-22 | — | — | US | disclosed |
| US-20160264726-A1 | HIGH-FLUIDITY POLYCARBONATE COPOLYMER, PROCESS FOR PRODUCTION HIGHLY POLYMERIZED AROMATIC POLYCARBONATE RESIN AND AROMATIC POLYCARBONATE COMPOUND | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2016-09-15 | — | — | US | disclosed |
| US-9353216-B2 | High-fluidity polycarbonate copolymer, process for production highly polymerized aromatic polycarbonate resin and aromatic polycarbonate compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2016-05-31 | — | — | US | disclosed |
| US-20150239889-A1 | PYRAZOLOPYRIMIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-08-27 | — | — | US | disclosed |
| US-20150232613-A1 | METHOD FOR PRODUCING BRANCHED AROMATIC POLYCARBONATE RESIN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2015-08-20 | — | — | US | disclosed |
| EP-2883899-A1 | METHOD FOR PRODUCING BRANCHED AROMATIC POLYCARBONATE RESIN | Mitsubishi Gas Chemical Company, Inc. (JP) | 2015-06-17 | — | — | EP | disclosed |
| US-8969505-B2 | Process for manufacturing branched aromatic polycarbonate resin with desired degree of branching | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2015-03-03 | — | — | US | disclosed |
| US-20140371404-A1 | METHOD FOR CONTINUOUS PRODUCTION OF HIGH-MOLECULAR-WEIGHT POLYCARBONATE RESIN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-12-18 | — | — | US | disclosed |
| US-20140206826-A1 | HIGH-FLUIDITY POLYCARBONATE COPOLYMER, PROCESS FOR PRODUCTION HIGHLY POLYMERIZED AROMATIC POLYCARBONATE RESIN AND AROMATIC POLYCARBONATE COMPOUND (AS AMENDED) | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-07-24 | — | — | US | disclosed |
| US-8273767-B2 | Bicyclic-substituted amines as histamine-3 receptor ligands | ABBOTT LABORATORIES (US) | 2012-09-25 | — | — | US | disclosed |
| US-7947711-B2 | Bicyclic-substituted amines as histamine-3 receptor ligands | ABBOTT LABORATORIES (US) | 2011-05-24 | — | — | US | disclosed |
| US-20110098285-A1 | BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2011-04-28 | — | — | US | disclosed |
| US-20090054420-A1 | BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2009-02-26 | — | — | US | disclosed |
| US-7456196-B2 | Bicyclic-substituted amines as histamine-3 receptor ligands | ABBOTT LABORATORIES (US) | 2008-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098285-A1 | BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS | HRH3, HRH4, HRH2 | CYP2A6 1355/4885CYP1A2 1051/4885KDM4E 3344/4885 |
| US-20090054420-A1 | BICYCLIC-SUBSTITUTED AMINES AS HISTAMINE-3 RECEPTOR LIGANDS | HRH3, HRH4, HRH2 | CYP2A6 1355/4885CYP1A2 1051/4885KDM4E 3344/4885 |
| US-20150239889-A1 | PYRAZOLOPYRIMIDINE COMPOUND | HIF1AN, EGLN2, EGLN3 | CYP2A6 279/4885CYP1A2 341/4885KDM4E 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.