Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.60 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12629700 | 0.90 | TRPV1 (0.62) | TRPV1MAPK3MAOAKCNH2 | |
| SCHEMBL12629706 | 0.90 | TRPV1 (0.69) | TRPV1MAPK3MAOAKCNH2 | |
| SCHEMBL12629698 | 0.87 | TRPV1 (0.51) | TRPV1MAPK3MAOAKCNH2 | |
| SCHEMBL1857034 | 0.86 | TRPV1 (0.64) | TRPV1MAPK3 | |
| SCHEMBL1860813 | 0.84 | TRPV1 (0.61) | TRPV1MAPK3 | |
| SCHEMBL12629883 | 0.83 | TRPV1 (0.61) | TRPV1MAPK3MAOAKCNH2 | |
| SCHEMBL1860874 | 0.83 | TRPV1 (0.60) | TRPV1MAPK3 | |
| SCHEMBL4359835 | 0.82 | TRPV1 (0.79) | TRPV1MAPK3 | |
| SCHEMBL12629696 | 0.82 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL1859378 | 0.81 | TRPV1 (0.73) | TRPV1MAPK3MAOAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935702-B2 | Substituted biaryl quinolin-4-ylamine analogues | NEUROGEN CORPORATION (US) | 2011-05-03 | — | — | US | disclosed |