⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10617888 | 0.54 | — | — | |
| Ethyne SCHEMBL18558 | 0.54 | — | — | |
| SCHEMBL570720 | 0.53 | — | — | |
| SCHEMBL140982 | 0.50 | — | — | |
| SCHEMBL131528 | 0.50 | — | — | |
| SCHEMBL5632709 | 0.50 | — | — | |
| SCHEMBL30500541 | 0.50 | — | — | |
| SCHEMBL1767056 | 0.50 | — | — | |
| SCHEMBL11093349 | 0.50 | — | — | |
| SCHEMBL8987212 | 0.43 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9291625-B2 | Diagnostic methods for determining prognosis of non-small cell lung cancer | ABBOTT LABORATORIES (US) | 2016-03-22 | — | — | US | disclosed |
| US-20120264635-A1 | DETECTION OF CHROMOSOMAL ABNORMALITIES ASSOCIATED WITH PROGNOSIS OF NON SMALL CELL LUNG CANCER | ABBOTT MOLECULAR INC. | 2012-10-18 | — | — | US | disclosed |
| US-20110105341-A1 | Diagnostic Methods For Determining Prognosis Of Non-Small Cell Lung Cancer | ABBOTT LABORATORIES (US) | 2011-05-05 | — | — | US | disclosed |
| US-20070048738-A1 | Methods and compositions for diagnosis, staging and prognosis of prostate cancer | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2007-03-01 | — | — | US | disclosed |