Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.61 |
| ▸ | PPARG | P37231 | 6/20 | 0.61 |
| ▸ | PPARD | Q03181 | 4/20 | 0.61 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12634663 | 0.92 | PPARA (0.60) | PPARAPPARGPPARDPTGER4PTGER2 | |
| SCHEMBL12636546 | 0.92 | PPARA (0.61) | PPARAPPARGPPARDPTGER4PTGER2 | |
| SCHEMBL12635643 | 0.91 | PPARA (0.57) | PPARAPPARGPPARDPTGER4PTGER2 | |
| SCHEMBL12636184 | 0.90 | PPARA (0.59) | PPARAPPARGPPARDPTGER4PTGER2 | |
| SCHEMBL12634655 | 0.89 | PPARA (0.58) | PPARAPPARGPPARDPTGER4PTGER2 | |
| SCHEMBL12634671 | 0.86 | PPARA (0.55) | PPARAPPARGPPARDPTGER4PTGER2 | |
| SCHEMBL12634630 | 0.84 | PPARA (0.59) | PPARAPPARGPPARDPTGER4PTGER2 | |
| SCHEMBL12634679 | 0.82 | PPARA (0.53) | PPARAPPARGPPARDPTGER4PTGER2 | |
| SCHEMBL12635645 | 0.81 | PPARA (0.59) | PPARAPPARGPPARDHPGDTP53 | |
| SCHEMBL12635603 | 0.81 | HTT (0.54) | PPARAPPARGPPARDTP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078370-A1 | NOVEL PARABANIC ACID DERIVATIVE AND DRUG HAVING THE SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |