Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.62 |
| ▸ | PPARG | P37231 | 8/20 | 0.62 |
| ▸ | PPARD | Q03181 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12635902 | 0.92 | PPARA (0.58) | PPARAPPARGPPARDHPGDTP53 | |
| SCHEMBL12636580 | 0.91 | PPARA (0.61) | PPARAPPARGPPARDHPGDTP53 | |
| SCHEMBL12635645 | 0.88 | PPARA (0.59) | PPARAPPARGPPARDHPGDTP53 | |
| SCHEMBL12635636 | 0.88 | PPARA (0.53) | PPARAPPARGPPARDHPGDTP53 | |
| SCHEMBL12635899 | 0.86 | PPARA (0.58) | PPARAPPARGPPARDHPGDTP53 | |
| SCHEMBL12636549 | 0.85 | PPARA (0.51) | PPARAPPARGPPARDHPGDHTT | |
| SCHEMBL12635630 | 0.85 | PPARA (0.52) | PPARAPPARGPPARDHTTALDH1A1 | |
| SCHEMBL12634630 | 0.84 | PPARA (0.59) | PPARAPPARGPPARDHTTPOLB | |
| SCHEMBL12635895 | 0.84 | PPARA (0.51) | PPARAPPARGPPARDHPGDHTT | |
| SCHEMBL12636568 | 0.83 | PTGER4 (0.52) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078370-A1 | NOVEL PARABANIC ACID DERIVATIVE AND DRUG HAVING THE SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |