Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12634546 | 0.89 | HTT (0.46) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL12636523 | 0.86 | KMT2A (0.52) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL12636475 | 0.84 | KMT2A (0.56) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL10341825 | 0.84 | KMT2A (0.57) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL12636499 | 0.82 | KMT2A (0.51) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL12635902 | 0.81 | PPARA (0.58) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL12635899 | 0.81 | PPARA (0.58) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL12635636 | 0.81 | PPARA (0.53) | KMT2AMEN1LMNAHTTPOLB | |
| SCHEMBL12635575 | 0.80 | GAA (0.51) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL12636169 | 0.80 | KMT2A (0.53) | KMT2AMEN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011078370-A1 | NOVEL PARABANIC ACID DERIVATIVE AND DRUG HAVING THE SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2011-06-30 | — | — | WO | disclosed |