SCHEMBL12636780

SCHEMBL12636780

CCn1cc(C#N)c(N=Nc2cnn(C)c2N)n1

nearest known ligand 0.31

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.31
HTT P42858 2/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP11B2 P19099 1/20 0.30
KDM4E B2RXH2 1/20 0.30
POLB P06746 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12636792 0.90 TLR8 (0.31)
SCHEMBL12636795 0.88 KDR (0.36) MAPTHTTALDH1A1TSHRKDM4E
SCHEMBL12636773 0.85 MAPT (0.33) MAPTHTTALDH1A1LMNATSHR
SCHEMBL12636787 0.78 CCNT1 (0.34) MAPTHTTALDH1A1POLBRECQL
SCHEMBL12636813 0.75 CCNT1 (0.32)
SCHEMBL12636778 0.75 MAPT (0.40) MAPTHTTALDH1A1LMNATSHR
SCHEMBL12636775 0.73 MAPT (0.49) MAPTHTTALDH1A1LMNATSHR
SCHEMBL12636789 0.70 MAPT (0.38) MAPTHTTALDH1A1LMNATSHR
SCHEMBL12636797 0.68 MAPT (0.36) MAPTHTTALDH1A1LMNATSHR
SCHEMBL12636794 0.68 CCNT1 (0.32) MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947625-B2 Ink sheet for heat-sensitive transfer recording material, heat-sensitive transfer recording method, ink cartridge and azo dye FUJIFILM CORPORATION (JP) 2011-05-24 US disclosed
US-7947625-B2 Ink sheet for heat-sensitive transfer recording material, heat-sensitive transfer recording method, ink cartridge and azo dye FUJIFILM CORPORATION (JP) 2011-05-24 US disclosed
US-20070202282-A1 Ink sheet for heat-sensitive transfer recording material, heat-sensitive transfer recording method, ink cartridge and azo dye FUJIFILM CORPORATION (JP) 2007-08-30 US disclosed
US-20070202282-A1 Ink sheet for heat-sensitive transfer recording material, heat-sensitive transfer recording method, ink cartridge and azo dye FUJIFILM CORPORATION (JP) 2007-08-30 US disclosed